New times for an old disease: intracranial mass lesions caused by Mycobacterium tuberculosis in 5 HIV-negative African immigrants

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Diego RipamontiFredy Suter

Abstract

The tuberculosis epidemic is still a global emergency, and its spread in the past 20 years has been fueled by the acquired immune deficiency syndrome pandemic and increasing drug resistance. International travel and migration may increase the incidence of tuberculosis in industrialized countries. We reviewed the clinical charts of patients admitted to the infectious diseases unit of Ospedali Riuniti (Bergamo, Italy) to identify patients with intracranial mass lesions caused by Mycobacterium tuberculosis. During the past 6.5 years, 5 of 30 patients with a mass of infectious origin in the brain had tuberculous brain lesions diagnosed. All 5 were human immunodeficiency virus (HIV)-negative adults and African immigrants. No patient had concomitant meningitis, 1 had a concomitant pulmonary disease, and 3 subjects reported a past history of tuberculosis. At presentation, no patient had fever and 3 had seizures. Examination of cerebrospinal fluid revealed normal findings for 4 of 4 subjects, and neuroimaging showed multiple intracranial mass lesions in 4 of 5 patients. The diagnosis was definite for 2 subjects (based on analysis of brain specimens) and presumptive for 3 subjects (1 had concomitant pulmonary tuberculosis, and 2 had cli...Continue Reading

References

Mar 1, 1978·Archives of Neurology·D R Whitener
Mar 1, 1991·Neurosurgery·A BouchamaE B Siqueira
Jan 1, 1989·British Journal of Neurosurgery·A R Choudhury
Apr 1, 1983·The American Journal of Medicine·E HarderP Carney
Aug 1, 1995·Tubercle and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·R RajeswariZ A Sayeed
Dec 1, 1993·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·S J KentA M Mijch
Apr 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A MoulignierB Dupont
Jun 1, 1996·Tubercle and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·L MonnoG Pastore
Apr 1, 1997·British Journal of Neurosurgery·V Rajshekhar, M J Chandy
Nov 14, 1997·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·G E Mathisen, J P Johnson
Oct 13, 1999·Neurologic Clinics·J C Garcia-Monco
Apr 4, 2002·The Journal of Infectious Diseases·Christopher DyeBrian G Williams
Jul 26, 2002·Clinical Neurology and Neurosurgery·M C SharmaC Sarkar
Jul 19, 2003·Revista Do Instituto De Medicina Tropical De São Paulo·José E VidalJoão F G S Coelho
Aug 23, 2003·Lancet·Héctor H GarcíaUNKNOWN Cysticercosis Working Group in Peru
Sep 19, 2003·Lancet·Thomas R FriedenChristopher Dye

❮ Previous
Next ❯

Citations

Apr 13, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·José E VidalRafi F Dauar
Jun 11, 2008·Journal of Forensic Sciences·Klára TöroEva Keller
Dec 2, 2006·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Yasemin ErsoyRiza Durmaz
Oct 3, 2018·Continuum : Lifelong Learning in Neurology·Felicia Chow
Oct 26, 2018·Expert Review of Anti-infective Therapy·Ravindra Kumar GargNeeraj Kumar
Sep 2, 2009·Microbiology and Molecular Biology Reviews : MMBR·Francesca GazzanigaCharles Brenner
Jun 10, 2011·Expert Review of Neurotherapeutics·Devender BhallaPierre-Marie Preux
Jun 24, 2016·Microbiology Spectrum·Andrea J ZimmerKaren C Bloch

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Antitubercular Agents (ASM)

Antitubercular agents are pharmacologic agents for treatment of tuberculosis. Discover the latest research on antitubercular agents here.

Antitubercular Agents

Antitubercular agents are pharmacologic agents for treatment of tuberculosis. Discover the latest research on antitubercular agents here.

Related Papers

The Journal of the American Board of Family Practice
A G OshinowoL L Golusinski
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
V B PatelT Mthiyane
© 2021 Meta ULC. All rights reserved