New use of primaquine for malaria

Médecine et maladies infectieuses
M OliverS Picot

Abstract

Primaquine is the only available drug to treat Plasmodium vivax liver stages (hypnozoites). It has been used for more than five decades and is now included in an increasing number of clinical guidelines. The major concern is induced hemolysis when administered to glucose-6-phosphate-dehydrogenase deficient patients. Primaquine could be used for causal prophylaxis during and after exposure or for presumptive antirelapse therapy (PART) in case of high exposure to P. vivax. A radical cure is used to avoid relapse for patients with a confirmed bloodstream infection with P. vivax or P. ovale. In France, primaquine is not approved for prevention and treatment and its use requires a specific temporary authorization.

References

Jun 1, 1985·British Journal of Clinical Pharmacology·G W MihalyA M Breckenridge
Jun 1, 1985·British Journal of Clinical Pharmacology·S A WardA M Breckenridge
Mar 1, 1994·Transactions of the Royal Society of Tropical Medicine and Hygiene·D BunnagT Harinasuta
Feb 1, 1993·British Journal of Clinical Pharmacology·G EdwardsN J White
Jun 5, 1999·Tropical Medicine & International Health : TM & IH·I S TantularF Kawamoto
Feb 16, 2000·Transactions of the Royal Society of Tropical Medicine and Hygiene·C LuxemburgerF Nosten
Mar 16, 2000·Transactions of the Royal Society of Tropical Medicine and Hygiene·M Rowland, N Durrani
Nov 17, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J K BairdUNKNOWN United States Naval Medical Research Unit 2 Clinical Trials Team
Mar 20, 2003·Trends in Parasitology·J Kevin Baird, Karl H Rieckmann
Jun 7, 2003·Tropical Medicine & International Health : TM & IH·Indah S Tantular, Fumihiko Kawamoto
Jul 21, 2004·Transactions of the Royal Society of Tropical Medicine and Hygiene·D D RajgorN A Kshirsagar
Oct 21, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J Kevin Baird, Stephen L Hoffman
Sep 6, 2005·Biochemical Pharmacology·Patrick G BrayLeann Tilley
May 26, 2006·British Journal of Clinical Pharmacology·Bui Tri CuongMichael D Edstein
Jul 25, 2006·The Journal of Infection·K M B Ajdukiewicz, E L C Ong
Jan 12, 2007·The Journal of Infection·David G LallooUNKNOWN HPA Advisory Committee on Malaria Prevention in UK Travellers

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Citations

Jul 16, 2009·Médecine sciences : M/S·Stéphane Picot, Anne-Lise Bienvenu
Jul 19, 2011·Emerging Infectious Diseases·Benjamin QueyriauxXavier Deparis
Jul 30, 2014·Travel Medicine and Infectious Disease·R MiglianiC Rapp
Aug 14, 2012·Tropical Medicine & International Health : TM & IH·Remington L Nevin
Oct 12, 2017·Critical Reviews in Food Science and Nutrition·Jin WangVijaya Raghavan

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