New Vision for Visual Prostheses

Frontiers in Neuroscience
Alexander Farnum, Galit Pelled

Abstract

Developments of new strategies to restore vision and improving on current strategies by harnessing new advancements in material and electrical sciences, and biological and genetic-based technologies are of upmost health priorities around the world. Federal and private entities are spending billions of dollars on visual prosthetics technologies. This review describes the most current and state-of-the-art bioengineering technologies to restore vision. This includes a thorough description of traditional electrode-based visual prosthetics that have improved substantially since early prototypes. Recent advances in molecular and synthetic biology have transformed vision-assisted technologies; For example, optogenetic technologies that introduce light-responsive proteins offer excellent resolution but cortical applications are restricted by fiber implantation and tissue damage. Other stimulation modalities, such as magnetic fields, have been explored to achieve non-invasive neuromodulation. Miniature magnetic coils are currently being developed to activate select groups of neurons. Magnetically-responsive nanoparticles or exogenous proteins can significantly enhance the coupling between external electromagnetic devices and any neurons...Continue Reading

References

Jul 1, 1992·Vision Research·K ChaR A Normann
Jan 1, 1992·The Journal of Physiology·A FerbertC D Marsden
Feb 1, 1992·IEEE Transactions on Bio-medical Engineering·P B Meijer
Jan 11, 1990·Nature·J W FassbinderH Vali
Feb 22, 1990·The Journal of Comparative Neurology·C A CurcioA E Hendrickson
May 1, 1990·Medical & Biological Engineering & Computing·M BakE M Schmidt
May 11, 1985·Lancet·A T BarkerI L Freeston
May 1, 1968·The Journal of Physiology·G S Brindley, W S Lewin
Mar 8, 1969·Nature·P Bach-y-RitaL Scadden
Jan 1, 1983·Anatomy and Embryology·R Hebel, H Holländer
Jan 1, 1994·Archives of Ophthalmology·M HumayunD Hickingbotham
Jan 1, 1996·Archives of Ophthalmology·M S HumayunD H Phillips
Mar 1, 1996·Journal of Neuroscience Methods·E J Tehovnik
Oct 17, 1998·IEEE Transactions on Bio-medical Engineering·C CapelleC Veraart
Sep 13, 2000·Nature·D WaldvogelM Hallett
Feb 27, 2001·Nature Neuroscience·A AmediE Zohary
Jun 1, 2001·Optometry and Vision Science : Official Publication of the American Academy of Optometry·J Stelmack
Jul 17, 2001·Brain Research·E SampaioP Bach-y-Rita
Mar 27, 2002·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·M L StruikR C Peters
Jun 13, 2002·Proceedings of the National Academy of Sciences of the United States of America·Oleg A SineshchekovJohn L Spudich
Jun 29, 2002·Science·Georg NagelPeter Hegemann
Dec 1, 1961·The Journal of Physiology·P M DANIEL, D WHITTERIDGE
Jul 6, 1963·Nature·H W LISSMANN, K E MACHIN
Nov 18, 2003·Artificial Organs·Claude VeraartJean Delbeke
Apr 6, 2004·Proceedings of the National Academy of Sciences of the United States of America·Pietro PietriniJames V Haxby
Apr 14, 2004·Archives of Ophthalmology·Alan Y ChowRonald Schuchard
Oct 16, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Keith A SchneiderSabine Kastner
May 7, 2005·Journal of Neural Engineering·Daniel PalankerStephen Baccus
May 7, 2005·Journal of Neural Engineering·M E BrelénC Veraart
May 12, 2005·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Wolfgang Wiltschko, Roswitha Wiltschko
Jul 12, 2005·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Manjunatha MahadevappaMark S Humayun
Aug 24, 2005·Nature Neuroscience·Edward S BoydenKarl Deisseroth
Apr 20, 2006·The British Journal of Ophthalmology·J B HassellJ E Keeffe
Apr 25, 2007·Proceedings of the National Academy of Sciences of the United States of America·John S Pezaris, R Clay Reid
May 29, 2007·Experimental Eye Research·L ColodettiM S Humayun
Oct 30, 2007·Neuron·Brian A WandellAlyssa A Brewer
Nov 17, 2007·Neuroreport·Daniel-Robert ChebatMaurice Ptito
Dec 14, 2007·Journal of the Royal Society, Interface·Steven HughesAlicia J El Haj
Jun 27, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Assaf A GiladJeff W M Bulte

❮ Previous
Next ❯

Citations

Feb 27, 2021·Frontiers in Human Neuroscience·Maurice PtitoDaniel-Robert Chebat
Apr 13, 2021·Journal of Medical Engineering & Technology·Léo Pio-LopezDamien Depannemaecker

❮ Previous
Next ❯

Methods Mentioned

BETA
cochlear implant
chip
light scattering
biosensing
targeted mutations

Clinical Trials Mentioned

NCT02556736
NCT03293524
NCT03326336

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Deutsche zahnärztliche Zeitschrift
H Weber
Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics
Soroush Niketeghad, Nader Pouratian
ANZ Journal of Surgery
Philip M LewisJeffrey V Rosenfeld
IEEE Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society
Larry Howard
© 2021 Meta ULC. All rights reserved