New World monkey Aotus nancymae as a model for Campylobacter jejuni infection and immunity

Infection and Immunity
Franca R JonesStephen E Walz

Abstract

Three groups of six monkeys (Aotus nancymae) each were inoculated intragastrically with increasing doses of Campylobacter jejuni. Infection resulted in fecal colonization (100% of monkeys), dose-related diarrhea, and robust immune responses. Colonization duration and diarrhea rate were reduced upon secondary challenge. A. nancymae may be useful for studying anti-Campylobacter vaccine efficacy.

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Citations

Jul 16, 2008·Clinical Microbiology Reviews·Riny JanssenRobert J Owen
Jan 21, 2010·Infection and Immunity·David R TribbleA Louis Bourgeois
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Jul 9, 2020·Science Advances·Benjamin K QuintelIan J Amanna
Jun 25, 2020·ACS Infectious Diseases·Maude Cloutier, Charles Gauthier

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