NG-Test Carba 5 for Rapid Detection of Carbapenemase-Producing Enterobacterales from Positive Blood Cultures

Antimicrobial Agents and Chemotherapy
Julie TakissianLaurent Dortet

Abstract

The immunochromatographic assay, NG-test Carba 5 (NG Biotech), has been evaluated for detection of carbapenemase-producing Enterobacterales (CPE) from spiked blood cultures (n = 205). It detected and discriminated in less than 30 minutes KPC, IMP, VIM, NDM, and OXA-48-like producers with a sensitivity and specificity of 97.7% and 96.1%, respectively. Thus, it might help the rapid optimization of treatment of bloodstream infections due to CPE.

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Citations

Jul 10, 2020·Lab on a Chip·Rathina Kumar ShanmugakaniSaurabh Mehta
Feb 23, 2020·The Journal of Antimicrobial Chemotherapy·Pierre BogaertsTe-Din Huang
Aug 12, 2020·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·William StokesDaniel Gregson
Sep 20, 2020·Journal of Chemotherapy·Carla Villarroel LoraCarlos Hernán Rodríguez
Nov 21, 2020·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Toru KanahashiMiki Nagao
Dec 12, 2020·The Journal of Antimicrobial Chemotherapy·Saoussen OueslatiThierry Naas
Feb 19, 2021·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Matteo BoattiniCristina Costa
Apr 21, 2021·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Ignacio TorresDavid Navarro
May 1, 2021·Expert Review of Molecular Diagnostics·Michael R JacobsDaniel D Rhoads
Oct 15, 2019·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·D R GiacobbeG M Rossolini
Oct 5, 2020·Infectious Disease Clinics of North America·Andrea EndimianiMichael R Jacobs
Aug 4, 2021·Microbial Biotechnology·Christian MoguetHervé Volland

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