PMID: 9502566Mar 21, 1998Paper

Nicardipine for hypertensive emergencies in children with renal disease

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
J MichaelJ D Tobias


Hypertensive emergencies secondary to renal diseases were treated with nicardipine in three children. Nicardipine is the first intravenously administered dihydropyridine calcium channel blocker. Its physiological actions include vasodilation, with limited effects on the chronotropic and inotropic function of the myocardium. Nicardipine, starting at 5 microg/kg per min and then continued at a maintenance infusion of 1-3 microg/kg per min, effectively controlled the mean arterial pressure in the three patients. Apart from occasional superficial thrombophlebitis in a fourth patient, no adverse effects were noted.


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Related Concepts

Calcium Channel Blockers
Emergency Care
Renal Hypertension
Intravenous Injections
Kidney Diseases

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