PMID: 9502566Mar 21, 1998Paper

Nicardipine for hypertensive emergencies in children with renal disease

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
J MichaelJ D Tobias

Abstract

Hypertensive emergencies secondary to renal diseases were treated with nicardipine in three children. Nicardipine is the first intravenously administered dihydropyridine calcium channel blocker. Its physiological actions include vasodilation, with limited effects on the chronotropic and inotropic function of the myocardium. Nicardipine, starting at 5 microg/kg per min and then continued at a maintenance infusion of 1-3 microg/kg per min, effectively controlled the mean arterial pressure in the three patients. Apart from occasional superficial thrombophlebitis in a fourth patient, no adverse effects were noted.

Citations

Oct 8, 2008·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Joseph T Flynn, Kjell Tullus
Jul 21, 2011·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Jayanthi Chandar, Gastón Zilleruelo
Mar 12, 2011·International Journal of Clinical Pharmacy·D G HornG Hempel
Apr 14, 2000·Current Opinion in Pediatrics·S Hellerstein
Jun 9, 2005·Pediatric Emergency Care·Erika Constantine, James Linakis
Mar 11, 2000·Pharmacotherapy·M E Temple, M C Nahata
Sep 6, 2011·Paediatric Drugs·Christopher A Thomas
Jan 15, 2008·Annals of Emergency Medicine·Craig W Belsha
Dec 12, 2000·Journal of Pediatric Health Care : Official Publication of National Association of Pediatric Nurse Associates & Practitioners·I Porto
Nov 7, 2007·Journal of Hypertension·Giacomo D SimonettiMario G Bianchetti
Nov 19, 2019·Mini Reviews in Medicinal Chemistry·Abhinav Prasoon MishraAwani Kumar Rai
Oct 3, 2018·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Tomáš SeemanMark Mitsnefes
Sep 12, 2020·Pediatric Cardiology·J D TobiasCatherine D Krawczeski
Nov 17, 2020·Frontiers in Pediatrics·Rupesh RainaDavid Kaelber
Jul 11, 2001·The Journal of Pediatrics·J T FlynnT E Bunchman

Related Concepts

Calcium Channel Blockers
Emergency Care
Renal Hypertension
Intravenous Injections
Kidney Diseases
Perdipine

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