PMID: 6971692Apr 6, 1981Paper

Nickel induction of Rosenthal fibers in rat brain

Brain Research
Y KressC Brosnan

Abstract

Nickel wire implants into the central nervous system of Lewis rats induces the formation of structures morphologically similar to Rosenthal fibers. The nickel-induced lesions are similar to those seen in Alexander's disease and other human conditions in which Rosenthal fibers are found. This is the first report on the induction of Rosenthal fibers in animals. It might be used to design animal models to study Rosenthal fiber formation and possibly Alexander's disease.

References

Sep 1, 1979·Journal of Toxicology and Environmental Health·M Lucassen, B Sarkar
Feb 1, 1978·Toxicology and Applied Pharmacology·F W SundermanI Damjanov
Sep 1, 1978·Journal of Neuropathology and Experimental Neurology·S Levine, R Sowinski
Jan 1, 1980·Acta Pathologica Japonica·S YamashiroH M Abandowitz

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Citations

Nov 26, 2002·Annals of Neurology·Michito NamekawaImaharu Nakano
Jan 1, 1991·Acta Neuropathologica·B LachT R Davie
Jan 1, 1982·Acta Neuropathologica·T L Hwang, A Borit
Aug 8, 1997·Neuroscience Letters·R J CastellaniM A Smith

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