Night blindness with depolarizing pattern of ON/OFF response in electroretinogram: a case report

Documenta Ophthalmologica. Advances in Ophthalmology
Tomoaki UsuiHaruki Abe

Abstract

To present a patient who has night blindness with a depolarizing pattern of ON/OFF response by electroretinography (ERG). A 43-year-old woman had had night blindness and poorly corrected visual acuity since childhood. Parental consanguinity was noted. The patient had suffered from mental retardation, epilepsy, and mild cerebellar ataxia. Corrected visual acuity was 20/30 in the right eye and 20/25 in the left. Goldmann perimetry showed no scotoma but slight depression with internal isoptors. No evidence for rod activity was observed by Goldmann-Weekers adaptometry. The ocular fundi appeared normal. Conventional full-field ERGs to scotopic (dim and bright flash) and photopic (bright flash and flicker) stimuli were recorded. Photopic ERG responses to long flash stimulation (200 ms) were also examined. The scotopic responses to dim flash were non-recordable, while those to bright flash were severely reduced. The photopic responses to bright flash were decreased. The amplitudes of flicker responses also were significantly decreased, and the implicit times of those responses were prolonged. Although the amplitudes of a- and d-waves to long flash stimulation were reduced, those of the b-wave were within normal range. The implicit tim...Continue Reading

References

Oct 1, 1995·Vision Research·D C Hood, D G Birch
Jan 1, 1996·Documenta Ophthalmologica. Advances in Ophthalmology·D C Hood, D G Birch
Jul 31, 1998·Archives of Ophthalmology·M A SandbergE L Berson
Sep 1, 2001·American Journal of Ophthalmology·T UsuiH Abe
Oct 1, 1956·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·A DE ROUCKG VERRIEST

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Citations

Jul 31, 2014·Documenta Ophthalmologica. Advances in Ophthalmology·Eric VukmanicPaul DeMarco
Jun 24, 2018·Documenta Ophthalmologica. Advances in Ophthalmology·Maja SustarAnthony G Robson

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