Nimesulide poisoning in white-rumped vulture Gyps bengalensis in Gujarat, India.

Environmental Science and Pollution Research International
Kanthan NambirajanShashikant Jadhav

Abstract

Population of white-rumped vulture has not recovered in India to a desired level even after diclofenac was banned in 2006. During 2019, there were two known separate incidents of white-rumped vulture mortality involving four white-rumped vultures in Gujarat. After post-mortem examinations, tissues of all four vultures were received for toxicological investigation at the National Centre for Avian Ecotoxicology, SACON. Tissues were screened for a set of toxic pesticides, and none of them was at detectable level. Subsequently, the tissues were analysed for thirteen NSAIDs and paracetamol. Of all the drugs tested, only nimesulide was detected in all the tissues (17-1395 ng/g) indicative of exposure. Visceral gout was also observed in all the four vultures during post-mortem. Residues of nimesulide in tissues with symptoms of gout indicated that the vultures died due to nimesulide poisoning. Although, other than diclofenac, many NSAIDs are suspected to be toxic to white-rumped vultures, only nimesulide is reported in the recent past with clear symptom of gout in wild dead white-rumped vultures similar to diclofenac. Since, nimesulide appears to act similar to diclofenac in exerting toxic effects, if veterinary use of nimesulide cont...Continue Reading

References

Jan 28, 2004·Nature·J Lindsay OaksAleem Ahmed Khan
Jan 27, 2006·PLoS Biology·Gerry SwanKerri Wolter
Jul 17, 2009·Environmental Science & Technology·Mark A TaggartDeborah J Pain
Sep 25, 2010·Bulletin of Environmental Contamination and Toxicology·S Muralidharan, V Dhananjayan
Sep 1, 2006·Environmental Toxicology and Pharmacology·N C Prakash ReddyK Ananda Rao
Mar 1, 2007·Environmental Toxicology and Pharmacology·Richard CuthbertDevendra Swarup
Oct 11, 2014·Conservation Biology : the Journal of the Society for Conservation Biology·Irene ZorrillaNgaio Richards
Nov 19, 2014·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Richard J CuthbertRhys E Green
Mar 5, 2016·Conservation Biology : the Journal of the Society for Conservation Biology·T H GalliganV Naidoo
Nov 22, 2017·Archives of Environmental Contamination and Toxicology·Kanthan NambirajanS Manonmani
Nov 18, 2018·Environmental Toxicology and Pharmacology·Ibrahim Zubairu HassanVinny Naidoo
Mar 18, 2019·Environmental Toxicology and Pharmacology·Claudia EleniAntonio Battisti

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.