Nipple-sparing mastectomies: Clinical outcomes from a single academic institution

Molecular and Clinical Oncology
Barbara DullJulie A Margenthaler

Abstract

Nipple-sparing mastectomies (NSMs) are increasingly used in the surgical treatment of patients with breast cancer and for prevention of breast cancer. The present study was performed to review the outcomes of patients undergoing NSMs at a single large university setting. A retrospective chart review was performed on all patients undergoing NSMs from 2008-2014. Charts were reviewed for demographic data and patient characteristics. Tumor and breast size, cancer recurrence and complications were also evaluated. Descriptive statistics were utilized to summarize the findings. From 2008-2014, 110 patients underwent 197 NSMs. The mean patient age was 44.4 years (range, 20-77). The average body mass index was 24 (range, 18-47). Breast weight was available for 106 specimens, with a mean weight of 475.5 g (range, 124.1-1,625.0 g). Seventy-three NSMs were performed for cancer and 124 were performed prophylactically. The mean tumor width was 1.38 cm (range, 0-6.0 cm), with an average nipple to tumor distance of 5.87 cm (range, 2.93-10.0 cm). Three (4%) patients required removal of the nipple areolar complex (NAC) due to pathological extension of the tumor. A total of 34 (17.2%) complications occurred, including infections, hematomas and ni...Continue Reading

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Citations

Jan 28, 2020·Plastic and Reconstructive Surgery·Jordan D FreyNolan S Karp
Mar 28, 2020·Breast Cancer Research and Treatment·Antônio Luiz FrassonFernanda Barbosa
Feb 8, 2020·Journal of the American College of Surgeons·Julie A MargenthalerTerence M Myckatyn

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