Nissen fundoplication improves gastric motility in patients with delayed gastric emptying

Surgical Endoscopy
T M FarrellJ G Hunter

Abstract

Fundoplication hastens gastric emptying in pediatric patients with gastroesophageal reflux disease (GERD). However, among adult GERD patients with impaired gastric emptying, the degree of improvement offered by fundoplication and the value of pyloroplasty are less well defined. Therefore, we compared outcomes in GERD patients with delayed gastric emptying after fundoplication alone or fundoplication with pyloroplasty. Of 616 consecutive GERD patients who submitted to primary fundoplication (601 laparoscopic) between October 1991 and October 1997, 82 underwent preoperative solid-phase nuclear gastric emptying analysis. Of these, 25 had delayed gastric emptying (half-time >100 min). Of 12 patients with emptying half-times between 100 and 150 min, one underwent pyloroplasty at the time of Nissen fundoplication. Of 13 patients with emptying half-times >150 min, 11 had pyloroplasty at the time of Nissen fundoplication. Patients were asked to use a 0 ("none") to 4 ("incapacitating") scale to describe the severity of their symptoms of heartburn, regurgitation, dysphagia, bloating and diarrhea preoperatively and at 6 weeks and 1 year postoperatively. Eight patients consented to a postoperative analysis of gastric emptying. One year aft...Continue Reading

References

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Citations

Sep 22, 2007·Current Gastroenterology Reports·Mehnaz A Shafi, P Jay Pasricha
Jun 2, 2005·The Surgical Clinics of North America·Pavlos Papasavas
Jun 12, 2003·Gastrointestinal Endoscopy Clinics of North America·George Triadafilopoulos
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Dec 21, 2019·Neuromodulation : Journal of the International Neuromodulation Society·Yedong HuWei-Fen Xie
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Jul 28, 2019·Current Gastroenterology Reports·Semeret MunieJon C Gould

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