PMID: 9420811Jul 1, 1995Paper

Nitrate-augmented myocardial imaging for assessment of myocardial viability

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
Z X HeX J Liu

Abstract

201Tl myocardial perfusion imaging is presently done by several possible strategies. Stress/delayed redistribution, stress/redistribution/reinjection, and rest/redistribution imaging can be useful in the clinical assessment of myocardial viability. Unfortunately, the extent of myocardial viability may still be underestimated even by 201Tl reinjection imaging, compared with 18F-fluorodeoxyglucose positron emission tomography. 99mTc-labeled sestamibi imaging provides results similar to those of 201Tl imaging in the detection of coronary artery disease, but several previous studies suggest that stress/rest 99mTc-labeled sestamibi imaging significantly underestimates myocardial viability. Recently it has been reported that the administration of nitrates, before 201Tl reinjection, improves detection of defect reversibility. Several studies also suggested that administration of nitrates before the injection of 99mTc-labeled sestamibi significantly improved detection of reversibility with this agent, whereas additional studies showed further that this combination improves the predictive accuracy for recovery of left ventricular function and perfusion after coronary revascularization, compared with a standard rest 99mTc-labeled sestami...Continue Reading

References

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Citations

Feb 2, 2002·Current Atherosclerosis Reports·Dinesh K Kalra, William A Zoghbi
Dec 12, 2003·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Wei HeAlberto Cuocolo
Oct 31, 1998·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·A PeixD García-Barreto
Oct 31, 1998·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Z X He, M S Verani
Jan 16, 1999·Clinical Nuclear Medicine·S S WadhwaV B Fernandes
Apr 10, 2009·Nuclear Medicine Communications·Min-Fu YangZuo-Xiang He
May 29, 2018·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Sharmila DorbalaR Glenn Wells

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