Nitric oxide and related factors linked to oxidation and inflammation as possible biomarkers of heart failure

Clínica e investigación en arteriosclerosis : publicación oficial de la Sociedad Española de Arteriosclerosis
Roberto Bonafede, Walter Manucha

Abstract

As a prevalent cardiovascular disease, heart failure is one of the leading causes of morbidity and premature mortality. Therefore, there is a special interest in the study of efficient markers associated with risk and / or prediction of cardiovascular events. Multiple candidates are proposed, especially those involved in oxidative and inflammatory processes typical of cardiovascular disease, such as superoxide anion, nitric oxide, and peroxynitrite. There is a lack of knowledge on the potential usefulness of these systems as biomarkers. This review aims to contribute to a better understanding of these systems, as well as an improved patient profile. Furthermore, a deep knowledge of these complex systems would also allow proposing new lines of research for the development of new therapeutic tools as a promising start for new approaches to this disease.

Citations

Oct 16, 2018·Immunological Investigations·Josef FontanaVaclav Vetvicka

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