Nitric oxide in follicle development and oocyte competence

Reproduction : the Official Journal of the Society for the Study of Fertility
G Basini, F Grasselli

Abstract

Apart from its well-known role in regulating endothelial function, in mammals, nitric oxide (NO) is an important signaling molecule involved in many processes, regulating different biological functions. It has been demonstrated that NO plays a role in the physiology of the reproductive system, where it acts in controlling the activity of reproductive organs in both sexes. In the female of several animal species, experimental data suggest the presence of an intraovarian NO-generating system, which could be involved in the control of follicular development. The role of NO in regulating follicular atresia by apoptosis is still controversial, as a dual action depending mostly on its concentration has been documented. NO also displays positive effects on follicle development and selection related to angiogenic events and it could also play a modulatory role in steroidogenesis in ovarian cells. Both in monovulatory and poliovulatory species, the increase in PGE2 production induced by NO via a stimulatory effect on COX-2 activity appears to be a common ovulatory mechanism. Considerable evidence also exists to support an involvement of the NO/NO synthase system in the control of meiotic maturation of cumulus-oocyte complexes.

References

Dec 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·L J IgnarroG Chaudhuri
Jun 15, 1995·Biochemical and Biophysical Research Communications·L KobzikJ S Stamler
Aug 1, 1995·Nature Medicine·J L ZweierP Kuppusamy
Mar 1, 1997·Fertility and Sterility·J S HeslaA M Dharmarajan
Apr 1, 1997·Molecular Human Reproduction·M MasudaT Aso
Jun 11, 1998·Human Reproduction Update·M RosselliR K Dubey
Apr 17, 1999·Journal of the Society for Gynecologic Investigation·A Jablonka-ShariffL M Olson
May 13, 1999·Biochimica Et Biophysica Acta·J W Denninger, M A Marletta
Dec 10, 1999·Reproduction, Fertility, and Development·G BasiniC Tamanini
Mar 14, 2000·The Journal of Biological Chemistry·B L GodberR Harrison
May 2, 2001·The Journal of Obstetrics and Gynaecology Research·H Tobai, I Nishiya
Aug 24, 2001·Domestic Animal Endocrinology·F GrasselliC Tamanini
Oct 2, 2001·Prostaglandins & Other Lipid Mediators·G Basini, C Tamanini
Mar 14, 2002·Molecular Reproduction and Development·Se-Jin YoonKyung-Ah Lee
Sep 28, 2002·Human Reproduction·Kenrokuro MitsubeMats Brännström
Oct 23, 2002·Biology of Reproduction·Yasuhiko NakamuraHiroshi Kato
Dec 5, 2002·Reproduction in Domestic Animals = Zuchthygiene·F GrasselliC Tamanini
Mar 11, 2003·Endocrine Journal·Yoshiaki YamagataHiroshi Kato
Sep 16, 2003·Molecular and Cellular Endocrinology·Shumin BuBo Zhou
Jun 5, 2004·Regulatory Peptides·Giuseppina BasiniCarlo Tamanini
Jun 30, 2005·Zygote : the Biology of Gametes and Early Embryos·Yong TaoGuoliang Xia
Sep 30, 2006·Reproduction : the Official Journal of the Society for the Study of Fertility·Anna T Grazul-BilskaDale A Redmer
Jan 16, 2007·European Journal of Endocrinology·Félix VargasJoaquín García-Estañ
Feb 20, 2007·Animal Reproduction Science·N R SundaresanK A Ahmed
Oct 30, 2007·Reproduction : the Official Journal of the Society for the Study of Fertility·Shan HerathI Martin Sheldon
Mar 14, 2008·Biology of Reproduction·Sagit Sela-AbramovichNava Dekel

❮ Previous
Next ❯

Citations

Oct 24, 2015·Reproductive Sciences·Giuseppina BasiniFrancesca Grasselli
Jun 28, 2017·Zygote : the Biology of Gametes and Early Embryos·Ramon Cesar BotigelliClaudia Lima Verde Leal
Apr 4, 2017·Reproduction, Fertility, and Development·Giuseppina BasiniFrancesca Grasselli
Aug 30, 2019·Cell and Tissue Research·Kaili XuCheng Zhang
Nov 2, 2019·Reproduction, Fertility, and Development·R CiccimarraG Basini
Oct 12, 2019·Free Radical Biology & Medicine·Irantzu Pérez-RuizJosé-Ignacio Ruiz-Sanz
Jan 28, 2021·International Journal of Environmental Research and Public Health·Maria Cristina Budani, Gian Mario Tiboni
Dec 25, 2019·Reproductive Toxicology·Laura Silveira AyresElizabeth Obino Cirne-Lima
Mar 5, 2021·Domestic Animal Endocrinology·G BasiniF Grasselli
Apr 18, 2021·Molecular and Cellular Biochemistry·Maryam EzzatiRaziyeh Kheirjou
Nov 26, 2019·Theriogenology·Alessia PacentraGiuseppina Basini
Jul 3, 2021·Animals : an Open Access Journal From MDPI·Francesca GrasselliGiuseppina Basini
Mar 2, 2018·Environmental Science & Technology·Rikke PoulsenMartin Hansen
Jun 11, 2020·Ecotoxicology and Environmental Safety·Yu-Qing GaoCheng-Guang Liang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis