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Nitrofurazone-reducing enzymes in E. coli and their role in drug activation in vivo

Canadian Journal of Microbiology

Oct 1, 1975

D R McCallaMing-Jen Fan

PMID: 136

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Abstract

Earlier work showed that Escherichia coli contains at least two enzymes which reduce nitrofurazone and other nitrofuran derivatives. One of these enzymes is lacking in some nitrofurazone-resistant mutant strains. We now report that there are three separable nitrofuran reductases in this...read more

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Nitrofurazone
Enzymes, antithrombotic
Enzymes, peripheral vasodilators
Mutant
Nitrofuran derivatives, antibacterials for systemic use
Oxidation-Reduction
Alloenzymes
Mutation Abnormality
DNA, Bacterial
Organism
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  • Nitrofurazone-reducing enzymes in E. coli and their role in drug activation in vivo

    Canadian Journal of Microbiology

    Oct 1, 1975

    D R McCallaMing-Jen Fan

    PMID: 136

    DOI:

    Abstract

    Earlier work showed that Escherichia coli contains at least two enzymes which reduce nitrofurazone and other nitrofuran derivatives. One of these enzymes is lacking in some nitrofurazone-resistant mutant strains. We now report that there are three separable nitrofuran reductases in this...read more

    Mentioned in this Paper

    Nitrofurazone
    Enzymes, antithrombotic
    Enzymes, peripheral vasodilators
    Mutant
    Nitrofuran derivatives, antibacterials for systemic use

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    • Citations26
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