PMID: 6111986Feb 1, 1981Paper

Nitrogen control in Pseudomonas aeruginosa: a role for glutamine in the regulations of the synthesis of nadp-dependent glutamate dehydrogenase, urease and histidase

Archives of Microbiology
D B JanssenC van der Drift

Abstract

In Pseudomonas aeruginosa the formation of urease, histidase and some other enzymes involved in nitrogen assimilation is repressed by ammonia in the growth medium. The key metabolite in this process appears to be glutamine or a product derived from it, since ammonia and glutamate did not repress urease and histidase synthesis in a mutant lacking glutamine synthetase activity when growth was limited for glutamine. The synthesis of these enzymes was repressed in cells growing in the presence of excess glutamine. High levels of glutamine were also required for the derepression of NADP-dependent glutamate dehydrogenase formation in the glutamine synthetase-negative mutant.

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Citations

Jan 1, 1982·Zeitschrift für allgemeine Mikrobiologie·C ZornH Kaltwasser
Jan 1, 1989·Archives of Microbiology·G Mörsdorf, H Kaltwasser
Aug 1, 1982·Archives of Microbiology·L MeileT Leisinger
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May 17, 2019·Journal of Breath Research·William R Bishai, Graham S Timmins
Aug 12, 2018·The ISME Journal·Alvaro San MillanR Craig MacLean
Nov 1, 1985·Journal of Bacteriology·C Vander Wauven, V Stalon
Nov 1, 1985·Journal of Bacteriology·R Craven, T C Montie
Sep 1, 1982·Journal of Bacteriology·D B JanssenC van der Drift
Aug 1, 1988·Journal of Bacteriology·B L PasloskeW Paranchych

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