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NMR analyses on the molecular mechanism of the conformational rigidity of 2-thioribothymidine, a modified nucleoside in extreme thermophile tRNAs

FEBS Letters

Jun 27, 1983

Y YamamotoS Higuchi

PMID: 6190675

Abstract

1H-NMR analyses have been made on the conformations of 2-thioribothymidine (s2T), 2-thiodeoxyribothymidine (s2dT), as well as ribothymidine (T) and deoxyribothymidine (dT). s2T and s2dT exclusively take the anti form rather than the syn form. The C3'-endo-gg form of the sugar moiety is ...read more

Mentioned in this Paper

In Vivo NMR Spectroscopy
RNA Conformation
Structure-Activity Relationship
Butyribacterium
Transfer RNA
Thiouridine
RNA, Bacterial
2-thioribothymidine
Paper Details
References
  • References6
  • Citations15
12

NMR analyses on the molecular mechanism of the conformational rigidity of 2-thioribothymidine, a modified nucleoside in extreme thermophile tRNAs

FEBS Letters

Jun 27, 1983

Y YamamotoS Higuchi

PMID: 6190675

DOI:

Abstract

1H-NMR analyses have been made on the conformations of 2-thioribothymidine (s2T), 2-thiodeoxyribothymidine (s2dT), as well as ribothymidine (T) and deoxyribothymidine (dT). s2T and s2dT exclusively take the anti form rather than the syn form. The C3'-endo-gg form of the sugar moiety is ...read more

Mentioned in this Paper

In Vivo NMR Spectroscopy
RNA Conformation
Structure-Activity Relationship
Butyribacterium
Transfer RNA
Thiouridine
RNA, Bacterial
2-thioribothymidine

Related Papers

Paper Details
References
  • References6
  • Citations15
12
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