No benefit of extended mesenteric resection with central vascular ligation in right-sided colon cancer

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland
F OlofssonI Syk

Abstract

The optimal extent of mesenteric resection in colon cancer surgery is not known. We have previously shown an increased mortality associated with wider mesenteric resection in right hemicolectomy. This study compares the short- and long-term outcome in three variations of right hemicolectomy based on the position of the vascular ligature in the mesentery. In all, 2084 cases of cancer in the caecum or ascending colon were identified in the Swedish Colorectal Cancer Registry and categorized according to the position of the vascular ligature: central ligation of ileocolic vessels (ICVs) ± right colic vessels (n = 390), central ligation of ICVs + right branch of middle colic vessels (MCVs) (n = 1360) and central ligation of ICVs + central ligation of MCVs (n = 334). Neither 3-year overall survival, 3-year disease-free survival nor local recurrence rate differed between the groups (P = 0.604; P = 0.247; P = 0.237). There was still no difference after multivariate analysis adjusted for age, sex, American Society of Anesthesiologists classification, TNM stage and adjuvant therapy. An increased peri-operative mortality, however, was observed in extended mesenteric resections, increasing from 0.8% in non-extended to 3.6% in more extended...Continue Reading

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Citations

Jan 25, 2017·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·D Miskovic
Mar 24, 2017·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·F OlofssonI Syk
Nov 2, 2017·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·R BernhoffA Martling
Jul 25, 2018·Minerva chirurgica·Abe FingerhutSelman Uranues
Nov 16, 2018·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Corrado PedrazzaniAlfredo Guglielmi
Mar 8, 2021·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Zutoia BalciscuetaÁlvaro García-Granero
Apr 30, 2020·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Jonathan B YuvalJulio Garcia-Aguilar
May 3, 2021·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Jasmine CraneAdam T Stearns

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