No difference in responsiveness to a low dose of alcohol between healthy women and men

Pharmacology, Biochemistry, and Behavior
Sigrid NybergInger Sundström Poromaa

Abstract

The purpose of the current study was to examine gender-related differences in alcohol responsiveness by comparing the effect of a low-dose intravenous alcohol infusion upon saccadic eye movements, self-rated sedation and intoxication scores. The functional sensitivity to a low dose of alcohol in 12 healthy women and 12 healthy men was evaluated by comparing the effects of an intravenous alcohol infusion on a number of saccadic eye movement measures, including saccadic eye velocity (SEV), saccade latency, saccade accuracy, saccade deceleration and self-rated levels of intoxication and sedation. The infusion of a low dose of alcohol induced a decrease in SEV and increased saccade deceleration and self-rated scores of intoxication in both males and females. Saccade accuracy was also significantly deteriorated by alcohol in both groups. The alcohol infusion did not induce any main gender-related differences in the saccade or visual analogue scale measurements. According to the findings of the present study, no gender differences in the responsiveness to a low-dose alcohol infusion were found.

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Citations

Sep 30, 2009·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Melissa A MillerMark T Fillmore
Nov 29, 2008·Aging Clinical and Experimental Research·John F Greany, Richard P Di Fabio
Oct 12, 2013·Journal of Forensic and Legal Medicine·Kai-Uwe SchmittUrs Schwarz
Aug 10, 2005·Alcoholism, Clinical and Experimental Research·Robert H PurdyTorbjörn Bäckström
Feb 3, 2011·British Journal of Clinical Pharmacology·Remco W M ZoethoutJoop M A van Gerven
Jan 24, 2009·Journal of Psychopharmacology·G J H DumontR J Verkes
Jun 2, 2011·Cephalalgia : an International Journal of Headache·M CambronL Crevits

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