No effect of pulsed electromagnetic fields on PC12 and HL-60 cells.

Radiation and Environmental Biophysics
Werner Sontag, D Kalka

Abstract

The effect of pulsed electromagnetic fields (PEMF) similar to those used in transcranial magnetic stimulation (TMS) on two tumour cell lines, the human promyelocytic leukaemia cell line (HL-60) and the rat pheochromocytoma cell line (PC12), was investigated. The two cell lines were exposed to non-homogeneous pulsed electromagnetic fields (about 0.25-4.5 T peak magnetic field strength; 1-8 exponential pulses, 0.25 Hz) at different positions on the coil (2x25 mm). After exposure with various intensities, various numbers of pulses and at different coil positions, cell viability and the intracellular cyclic AMP content were determined in the two cell lines. Additionally, in HL-60 cells the intracellular Hsp72 content and in PC12 cells the release of the neurotransmitters dopamine, noradrenaline and acetylcholine were measured after PEMF treatment. The results of these analyses do not hint at alterations in the cell viability or in the content of cAMP, Hsp72, dopamine, noradrenaline, and acetylcholine in the two tumour cell lines after PEMF exposure under various conditions.

References

May 11, 1985·Lancet·A T BarkerI L Freeston
Jan 1, 1995·International Review of Cytology·E M GoodmanM T Marron
Jan 1, 1994·Radiation and Environmental Biophysics·G KnedlitschekH Dertinger
Jul 22, 1998·Cell Stress & Chaperones·R Goodman, M Blank
Sep 15, 1998·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·L G CohenC Butefisch
Sep 22, 1998·Electroencephalography and Clinical Neurophysiology·P M Rossini, S Rossi
Nov 25, 1998·Journal of Cellular Biochemistry·L HanR Goodman
Feb 17, 2001·Journal of Cellular Biochemistry·H LinR Goodman
Aug 21, 2001·Biochemical and Biophysical Research Communications·C GarridoG Kroemer
May 14, 2004·Molecular Immunology·Zoltán Prohászka, George Füst

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Citations

May 13, 2011·European Archives of Psychiatry and Clinical Neuroscience·Julian HellmannGolo Kronenberg
Jul 27, 2007·International Journal of Radiation Biology·Werner Sontag, Dorothee Kalka
Jul 11, 2013·Journal of Neural Engineering·Hieu T NguyenChristine E Schmidt
Oct 23, 2015·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Hua LiuXiao-Lin Huang
Jan 15, 2014·International Journal of Biological Macromolecules·Ali AfrasiabiShahin Ahmadian

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