No evidence for impaired 'theory of mind' in unaffected first-degree relatives of schizophrenia patients

Acta Psychiatrica Scandinavica
Oguz KelemenZoltán Janka

Abstract

The aim of this study was to investigate the possibility that 'theory of mind' (ToM) impairments are associated with schizophrenia liability. Forty healthy control subjects and 79 first-degree biological relatives of schizophrenia patients (32 siblings and 47 parents) received the Eyes Test, during which subjects are asked to choose the word best describes the mental state of a person whose eyes are depicted on a photograph. The affected relatives (n = 14) performed worse on the Eyes Test compared with the controls (P = 0.0001), whereas the unaffected relatives (n = 65) showed intact performances (P = 0.4). The Eyes Test values did not correlate with age and IQ. There was no significant difference between male and female participants. ToM deficits, as measured by the Eyes Test, are not associated with schizophrenia liability.

References

May 1, 1996·Psychological Medicine·C D Frith, R Corcoran
May 24, 2000·Acta Psychiatrica Scandinavica. Supplementum·P F Liddle
Dec 6, 2000·Journal of Psychiatric Research·J M KingtonJ Williams
Mar 10, 2001·Psychological Medicine·G J Pickup, C D Frith
Mar 31, 2001·Journal of Child Psychology and Psychiatry, and Allied Disciplines·S Baron-CohenI Plumb
Apr 5, 2002·Neuropsychologia·Andrew J CalderAndrew W Young
Feb 14, 2003·Trends in Cognitive Sciences·Helen L. Gallagher, Christopher D. Frith
Jun 26, 2003·Acta Psychiatrica Scandinavica·I JanssenJim van Os
Jan 27, 2004·Schizophrenia Research·Kimmy S KeeMichael F Green

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Citations

Aug 24, 2006·European Archives of Psychiatry and Clinical Neuroscience·Yumiko InoueShigenobu Kanba
Dec 16, 2006·European Archives of Psychiatry and Clinical Neuroscience·Emre BoraBaybars Veznedaroglu
Sep 6, 2011·European Archives of Psychiatry and Clinical Neuroscience·Christiane MontagJürgen Gallinat
Feb 5, 2013·Psychiatry Research·Marie-Audrey LavoieAmélie M Achim
Jun 27, 2008·The Behavioral and Brain Sciences·Bernard Crespi, Christopher Badcock
Aug 3, 2005·Neuropsychology·Oguz KelemenSzabolcs Kéri
Jan 17, 2012·Personality Disorders·Lori N ScottMichael T Stevenson
Apr 17, 2009·Cognitive Neuropsychiatry·Maria Unenge HallerbäckChristopher Gillberg
Jan 6, 2012·Cognitive Neuropsychiatry·A D PentarakiR M Murray
Jan 25, 2012·Psychopathology·Inmaculada Ibanez-Casas, Jorge A Cervilla
Sep 12, 2013·Molecular Autism·Enrique G Fernández-AbascalSimon Baron-Cohen
Jan 8, 2014·Social Cognitive and Affective Neuroscience·David Dodell-FederChristine I Hooker
Sep 6, 2015·Social Cognitive and Affective Neuroscience·Sebastian MohnkeHenrik Walter
Nov 23, 2013·Comprehensive Psychiatry·Gábor CsuklyJános Réthelyi
May 21, 2011·Psychiatry Research·Diane Carol Gooding, Madeline Johnson Pflum
Jun 3, 2008·Psychiatry Research·Emre BoraBaybars Veznedaroglu
Feb 8, 2008·Schizophrenia Research·Shannon M CoutureDiana O Perkins
Jan 2, 2008·Psychiatry Research·Esther PousaJordi E Obiols
Dec 22, 2007·Schizophrenia Research·Yu Sun ChungJun Soo Kwon
Jul 5, 2005·Acta Psychiatrica Scandinavica·E BoraA Eryavuz
Nov 11, 2005·Acta Psychiatrica Scandinavica·H HakerW Rössler
Oct 22, 2011·Acta Psychiatrica Scandinavica·J MeijerUNKNOWN GROUP Investigators
Nov 10, 2006·Schizophrenia Research·Carol S Jahshan, Mark J Sergi
Aug 15, 2006·Psychiatry Research·Dominic MarjoramStephen Lawrie
Apr 8, 2006·Trends in Cognitive Sciences·Vaughan BellHadyn D Ellis
Apr 22, 2014·Psychiatry Research·Briana Cassetta, Vina Goghari
Dec 6, 2014·European Archives of Psychiatry and Clinical Neuroscience·Kesong HuShuchang He
Sep 14, 2014·Psychiatry Research·Marie-Audrey LavoieAmélie M Achim
Jun 24, 2010·Schizophrenia Research·Clare M GibsonAysenil Belger
Jun 17, 2008·Schizophrenia Research·Fabian AguirreCynthia A Levy
Oct 13, 2009·Schizophrenia Research·S AnselmettiR Cavallaro
Feb 28, 2015·Cognitive Neuropsychiatry·Matteo CellaTil Wykes

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