No evidence for major histocompatibility complex-dependent mating patterns in a free-living ruminant population

Proceedings. Biological Sciences
S Paterson, J M Pemberton

Abstract

Conventionally, the extraordinary diversity of the vertebrate major histocompatibility complex (MHC is thought to have evolved in response to parasites and pathogens affecting fitness. More recently, reproductive mechanisms such as disassortative mating have been suggested as alternative mechanisms maintaining MHC diversity. A large unmanaged population of Soay sheep (Ovis aries L.) was used to investigate reproductive mechanisms in the maintenance of MHC diversity. Animals were sampled as new-born lambs and between 887 and 1209 individuals were typed at each of five microsatellite markers located either within or flanking the ovine MHC. All loci were in Hardy-Weinberg proportions. A novel likelihood-based approach was developed to analyse mating patterns using paternity data. No evidence for non-random mating with respect to MHC markers was found using this technique. We conclude that MHC diversity in the St Kildan Soay sheep population is unlikely to be maintained by mating preferences and that, in contrast with evidence from experimental mice populations, MHC variation plays no role in the mating structure of this population.

References

Feb 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·A L Hughes, M Nei
May 14, 1987·Nature·P B SinghB Roser
Jul 1, 1983·Genetics·P W Hedrick, G Thomson
Jun 1, 1995·Genetics·A M CrawfordS W Kappes
Jun 22, 1995·Proceedings. Biological Sciences·C WedekindA J Paepke
Nov 29, 1994·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·C Wedekind
Nov 29, 1994·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·W K PottsE K Wakeland
Jan 1, 1993·Annual Review of Immunology·J KleinN Takahata
Jun 1, 1993·Clinical Immunology and Immunopathology·B S Nepom
Apr 1, 1993·Trends in Genetics : TIG·J Trowsdale
Dec 22, 1995·Proceedings. Biological Sciences·I R Stevenson, D R Bancroft
May 1, 1996·Mammalian Genome : Official Journal of the International Mammalian Genome Society·E A LordG W Montgomery
Jun 29, 1996·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·J M PembertonT H Clutton-Brock
Mar 18, 1997·Proceedings of the National Academy of Sciences of the United States of America·A G SingerK Yamazaki
Oct 27, 1997·American Journal of Human Genetics·P W Hedrick, F L Black
Jan 1, 1997·Life Sciences·R W Carón, R P Deis
May 9, 1998·Proceedings of the National Academy of Sciences of the United States of America·S PatersonJ M Pemberton
Jun 20, 1998·Molecular Ecology·T C MarshallJ M Pemberton
Jun 1, 1990·Trends in Ecology & Evolution·W K Potts, E K Wakeland
Feb 1, 1996·Trends in Ecology & Evolution·D Ebert, W D Hamilton

❮ Previous
Next ❯

Citations

Aug 1, 1998·Trends in Ecology & Evolution·S V Edwards, P W Hedrick
May 5, 2005·Proceedings. Biological Sciences·David S RichardsonTorbjörn von Schantz
Apr 8, 2006·Proceedings. Biological Sciences·Camille BonneaudGabriele Sorci
Mar 28, 2009·Proceedings. Biological Sciences·Hilary C MillerCharles H Daugherty
Oct 12, 2012·Proceedings. Biological Sciences·Jennifer L BollmerLinda A Whittingham
Feb 14, 2002·Proceedings of the National Academy of Sciences of the United States of America·Lara S CarrollWayne K Potts
Aug 30, 2000·Molecular Ecology·T Tregenza, N Wedell
Nov 26, 2003·Journal of Evolutionary Biology·L Bernatchez, C Landry
Jan 23, 2016·Behavioral Ecology : Official Journal of the International Society for Behavioral Ecology·David J WrightDavid S Richardson
Aug 12, 2009·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Isabel G Fernandez-de-MeraChristian Gortazar
Jul 13, 2004·Molecular Ecology·Helena Westerdahl
Jul 31, 2013·Molecular Ecology·Elise HuchardPeter M Kappeler
May 25, 2010·Molecular Ecology·Elise HuchardGuy Cowlishaw
Nov 7, 2009·Journal of Evolutionary Biology·J M SetchellL A Knapp
Sep 24, 2004·Microbes and Infection·K Mathias WegnerThorsten B H Reusch
Dec 4, 2014·PloS One·Katarzyna KudukJacek Radwan
Sep 25, 2003·Evolution; International Journal of Organic Evolution·Daniel Garrigan, Philip W Hedrick
Aug 12, 2005·Heredity·S B Piertney, M K Oliver
Nov 4, 1998·Heredity·W C Jordan, M W Bruford
Sep 9, 2000·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·C Wedekind, D Penn
Feb 26, 2020·Proceedings. Biological Sciences·Piotr Bentkowski, Jacek Radwan
Sep 29, 1998·Heredity·W C Jordan, M W Bruford
Sep 15, 2018·Behavioral Ecology : Official Journal of the International Society for Behavioral Ecology·Jesyka Meléndez-RosaEileen A Lacey
Aug 30, 2018·PeerJ·Parice A BrandiesKatherine Belov
May 8, 2021·Molecular Ecology·Wei HuangJosephine M Pemberton

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.