No impact of a leucocyte depleting arterial line filter on patient recovery after cardiopulmonary bypass

Acta Anaesthesiologica Scandinavica
A SahlmanO J Rämö

Abstract

Contact of blood with foreign surfaces in the cardiopulmonary bypass (CPB) circuit induces an inflammatory response and immunosuppression which are associated with several organ dysfunctions following cardiac surgery. The aim of the present study was to evaluate clinical patient recovery after coronary artery bypass surgery (CABG) using CPB with leucocyte filtration or no arterial line filter. Sixty patients scheduled for CABG were randomly assigned to undergo CPB with a leucocyte depleting arterial line filter (Pall LG6) or no filter. Total leucocyte count and platelet count were determined before and after CPB. Values for blood urea nitrogen, serum creatine, serum sodium and potassium, serum osmolality, urine creatine, urine sodium and potassium, and urine osmolality were recorded at baseline, at 6 h and 24 h after CPB, and on the 5th postoperative day. Complement status was evaluated by measuring the levels of C3 and C4 before surgery and 24 h after CPB. Need for postoperative inotropic support was recorded, as was oxygen index prior to and after tracheal extubation. Times to awakening and tracheal extubation were noted, as were length of stay at the intensive care unit (ICU) and the hospital. Amount of chest drainage until ...Continue Reading

References

May 1, 1992·The Annals of Thoracic Surgery·Y J GuC R Wildevuur
Jun 1, 1995·The Journal of Thoracic and Cardiovascular Surgery·T MihaljevicM Turina
Dec 1, 1995·The Annals of Thoracic Surgery·R Englander, M G Cardarelli
Nov 1, 1996·Anesthesiology·A Herskowitz, D T Mangano
Oct 13, 1998·The Annals of Thoracic Surgery·J P GottR A Guyton
Jan 1, 1995·The Indian Journal of Chest Diseases & Allied Sciences·R AroraY Arora

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Citations

Jan 24, 2007·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Oliver WarrenThanos Athanasiou
Aug 2, 2007·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Oliver WarrenThanos Athanasiou
Jan 22, 2008·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Oliver J WarrenThanos Athanasiou
Dec 3, 2010·Interactive Cardiovascular and Thoracic Surgery·Anna Grace LobergJohn Dark
Dec 15, 2005·Scandinavian Cardiovascular Journal : SCJ·Juha KoskenkariTatu Juvonen
Mar 16, 2007·Heart, Lung & Circulation·Hou-Kiat LimFranklin L Rosenfeldt
Oct 3, 2019·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Alexander WahbaUNKNOWN EACTS/EACTA/EBCP Committee Reviewers
Oct 24, 2002·Current Opinion in Hematology·Walter H Dzik

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