No increased mortality in later life for cohorts born during famine

American Journal of Epidemiology
V KannistoJ W Vaupel

Abstract

Nutrition early in life may influence adult mortality. The fetal-origins hypothesis suggests that nourishment before birth and during the individual's infancy programs the development of risk factors for several important diseases of middle and old age. The present study was designed to evaluate the impact of extreme nutritional deprivation in utero and during infancy and early childhood on mortality in later life. The authors analyzed the survival of the cohorts born in Finland during the severe 1866-1868 famine and during the 5 years immediately preceding and 5 years immediately following the famine. The study included 331,932 individuals born prior to the famine, 161,744 born during the famine, and 323,321 born after the famine. The authors assessed survival by cohorts from birth to age 17 years and from age 17 to 40, 60, and 80 years, as well as average length of life after age 80 years. Survival from birth to age 17 years was significantly lower in cohorts born before and during the famine than in the cohorts born after the famine (males, 0.566 vs. 0.671, a difference of 0.105 (95% confidence interval (CI) 0.102-0.108); females, 0.593 vs. 0.692, a difference of 0.099 (95% CI 0.096-0.102)). At subsequent ages, including old...Continue Reading

Citations

Aug 10, 2006·The American Journal of Clinical Nutrition·Rachel R Huxley
Aug 10, 2007·Proceedings of the National Academy of Sciences of the United States of America·David M CutlerDouglas M Norton
Sep 12, 2009·Current Gerontology and Geriatrics Research·Deborah M SlobodaMark H Vickers
Jan 1, 2009·Cardiology Research and Practice·F Gloria-BottiniE Bottini
Jul 11, 2012·American Journal of Human Biology : the Official Journal of the Human Biology Council·Alain Gagnon
Feb 1, 2013·Journal of Developmental Origins of Health and Disease·K SaxtonR Catalano
Jun 17, 2015·Evolution, Medicine, and Public Health·Julie Baker PhillipsAntonis Rokas
Jan 6, 2017·Proceedings. Biological Sciences·Michael BrigaSimon Verhulst
Mar 7, 2002·Epidemiology·Ralph Catalano
Aug 19, 2014·Human Nature : an Interdisciplinary Biosocial Perspective·Shige Song
Aug 2, 2014·Journal of Developmental Origins of Health and Disease·A M Vaiserman
Sep 30, 2015·Biopreservation and Biobanking·Oxana P RotarAlexandra O Konradi
Dec 5, 2017·Journal of Developmental Origins of Health and Disease·S SadrzadehR C Painter
Feb 14, 1998·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·J W Vaupel
Sep 10, 2005·European Journal of Epidemiology·Rebecca C PainterO P Bleker
Feb 27, 2003·Aging Clinical and Experimental Research·Kevin Kinsella, Victoria A Velkoff
Sep 5, 2001·American Journal of Human Biology : the Official Journal of the Human Biology Council·Lars Olov BygrenGöran Broström
May 11, 2007·The American Journal of Clinical Nutrition·Rachel HuxleyRory Collins
Dec 16, 2011·The American Journal of Clinical Nutrition·Annet F M van AbeelenTessa J Roseboom
Dec 24, 2010·Population and Development Review·Mikko Myrskylä
Mar 26, 2010·Nature·James W Vaupel
Jan 12, 2011·Annual Review of Public Health·L H LumeyEzra Susser
Dec 10, 2015·Canadian Journal on Aging = La Revue Canadienne Du Vieillissement·Anna Nicińska, Małgorzata Kalbarczyk-Stęclik
Sep 25, 2015·Journal of Economic Literature·Dora Costa
Apr 1, 2013·Journal of Developmental Origins of Health and Disease·H A Hanson, K R Smith
Jul 1, 2011·The Journal of Economic Perspectives : a Journal of the American Economic Association·Douglas Almond, Janet Currie
Apr 6, 2017·Proceedings of the National Academy of Sciences of the United States of America·Nicolas ToddPierre Bougnères
Aug 8, 2001·Paediatric and Perinatal Epidemiology·T J RoseboomO P Bleker
Aug 24, 2007·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·Z A R OliveiraM A Barbieri
Oct 22, 2016·Population Studies·Jona Schellekens, Frans van Poppel
Aug 26, 2010·Population and Development Review·Michael Murphy
Jul 16, 2014·Population and Development Review·Nadine OuelletteJohn R Wilmoth
Jun 24, 2017·American Journal of Epidemiology·Kristine BelesovaPaul Wilkinson
May 8, 2018·Population and Development Review·Jessica Y HoDuncan Thomas
Jul 3, 2002·Aging Clinical and Experimental Research·Bernard Jeune
Apr 22, 2003·American Journal of Human Biology : the Official Journal of the Human Biology Council·Virpi Lummaa
Dec 1, 2017·Nutrition Reviews·Daniel J HoffmanDaniel B Hardy

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.