PMID: 8939052Dec 1, 1996Paper

NO nerves in a tapeworm. NADPH-diaphorase histochemistry in adult Hymenolepis diminuta

Parasitology
Margaretha K S GustafssonMaria Reuter

Abstract

The free radical nitric oxide (NO), which is synthesized by nitric oxide synthase (NOS), has recently been discovered to function as a neuronal messenger. The presence of NOS was detected in the nervous system of adult Hymenolepis diminuta with NADPH-diaphorase (NADPH-d) histochemistry. The NADPH-d histochemical reaction is regarded as a selective marker for NOS in neuronal tissue. NADPH-d staining was observed in nerve fibres in the main and minor nerve cords and the transverse ring commissures, and in cell bodies in the brain commissure, along the main nerve cords, in the suckers and the rostellar sac. NADPH-d staining was also observed in the wall of the internal seminal vesicle and the genital atrium. The pattern of NADPH-d staining was compared with that of the 5-HT immunoreactive nervous elements. The NADPH-d staining reaction and the 5-HT immunoreactivity occur in separate sets of neurons. This is the first time the NADPH-d reaction has been demonstrated in the nervous system of a flatworm, indicating that NOS is present and that NO can be produced at this level of evolution.

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Citations

Jul 15, 1999·International Journal for Parasitology·N B TereninaM K Gustafsson
Oct 12, 2001·Parasitology International·V TandonN Saha
Mar 30, 2006·Parasitology·P RibeiroN Patocka
Feb 17, 2000·Annals of the New York Academy of Sciences·T G GearyD P Thompson
Dec 23, 2004·Parasitology Research·Mikhail V OnufrievMargaretha K S Gustafsson
Jan 15, 1999·Molecular Neurobiology·M Colasanti, G Venturini
Oct 16, 2008·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Bidyadhar DasValerie A Ferro
Sep 12, 2006·Molecular and Biochemical Parasitology·Shanta M MesserliRobert M Greenberg
May 21, 2003·Parasitology Research·Margaretha K S GustafssonSergei O Movsessian
May 31, 2018·Journal of Parasitic Diseases : Official Organ of the Indian Society for Parasitology·V Tandon, B Das
Nov 18, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·M K GrahamJ G McGeown

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