No subacute thrombosis and femoral bleeding complications under full anticoagulation in 150 consecutive patients receiving non-heparin-coated intracoronary Palmaz-Schatz stents

American Heart Journal
S W LeeK K Chan

Abstract

Intracoronary stenting has been shown to have better immediate and long-term clinical outcomes and less restenosis than standard balloon angioplasty. However, the benefit was achieved at the cost of higher rates of coronary thrombosis, bleeding complications, the need for anticoagulation, and longer hospital stay. For the latter reasons there is a tendency to replace the anticoagulants by antiplatelet agents alone after stenting. However, we prospectively monitored 150 consecutive patients (133 men, 17 women, mean age 58.5 years) from two centers since February 1993. They all had coronary artery disease and underwent percutaneous implantation of non-heparin-coated Palmaz-Schatz coronary stents under a full but lower dose of anticoagulation. The femoral approach was used in all patients except one. In the 150 patients, 200 stents were implanted in 165 target arteries with 172 lesions. Stenting was performed without the guidance of intravascular ultrasonography; high-pressure poststenting inflation was used in only 17.3% of patients with less than optimal angiographic results. Coronary angiography was performed at baseline, immediately after the procedure, and after 6 months (mean 207 +/- 53.6 days SD) of stenting. The mean (+/-S...Continue Reading

References

Sep 4, 1976·Lancet·S OramP Armstrong
Feb 1, 1991·Journal of the American College of Cardiology·M NobuyoshiK Kim
May 1, 1991·Journal of the American College of Cardiology·R A SchatzE Topol
Nov 15, 1990·The American Journal of Cardiology·H D TheronC J Pepine
Dec 1, 1990·British Heart Journal·A H Gershlick, D P de Bono
May 1, 1995·Catheterization and Cardiovascular Diagnosis·M C MoriceP Joly
Aug 1, 1995·The American Journal of Cardiology·E J Topol

❮ Previous
Next ❯

Citations

Jul 23, 2003·The Journal of Surgical Research·Peter H LinStephen R Hanson
Oct 5, 2010·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·K E Juhani AiraksinenGregory Y H Lip
May 23, 2003·Journal of Vascular and Interventional Radiology : JVIR·Peter H LinStephen R Hanson

❮ Previous
Next ❯

Related Concepts

Related Feeds

Acute Stroke

A stroke occurs when blood supply to the brain is interrupted depriving the brain of oxygen and nutrients. This feed focuses cerebrovascular accidents including ischemic and paralytic stroke.