PMID: 3768213Oct 1, 1986Paper

Nocturnal angina: precipitating factors in patients with coronary artery disease and those with variant angina

British Heart Journal
A A QuyyumiK M Fox

Abstract

Factors precipitating nocturnal myocardial ischaemia were investigated in 10 patients with frequent daytime and nocturnal angina pectoris. Eight patients had fixed obstructive coronary artery disease or a low exercise threshold or both before the onset of ischaemia. Two patients had variant angina with normal coronary arteries and negative exercise tests. During sleep the electrocardiogram, electroencephalogram, electro-oculogram, electromyogram, chest wall movements, nasal airflow, and oxygen saturation were continuously measured. Forty two episodes of transient ST segment depression were recorded in the eight patients with coronary artery disease and 26 episodes of ST segment depression and elevation in the two patients with variant angina and normal coronary arteries. All episodes of ST segment depression in the former group of patients were preceded by an increase in heart rate as a result of arousal and lightening of sleep, bodily movements, rapid eye movement sleep, or sleep apnoea (one episode). In contrast, in the variant angina group no increase in heart rate, arousal, or apnoea preceded 23 of the 26 episodes of ST segment change. Thus increase in myocardial oxygen demand was important in precipitating nocturnal angina...Continue Reading

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Citations

Oct 1, 1994·Cardiovascular Drugs and Therapy·U Thadani, L H Opie
May 1, 1989·Physiology & Behavior·D A Kirby, R L Verrier
Jan 13, 1990·Lancet·P Collins, K M Fox
Nov 1, 1996·Journal of the American College of Cardiology·G A LanzaA Maseri
Nov 14, 1997·Journal of the American College of Cardiology·A RehmanA A Quyyumi
Aug 18, 2004·Sleep Medicine Reviews·M R BonsignoreG Bonsignore
Jun 17, 1998·Journal of Internal Medicine·R Asplund, H Aberg
Jul 1, 1994·Journal of Internal Medicine·R Asplund
May 7, 2010·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Doina GherghelRebekka Heitmar
Apr 1, 1994·Postgraduate Medical Journal·R ListonW T McNicholas
May 15, 1991·The American Journal of Cardiology·J BarryA P Selwyn
Jul 1, 1993·International Journal of Cardiology·R SteffensenS Haunsø
Aug 1, 1987·International Journal of Cardiology·T Gnecchi RusconeD Di Mattia
Jan 7, 2004·The American Journal of Medicine·Paolo MoruzziMauro Contini
Nov 15, 1989·Postgraduate Medicine·A Quyyumi

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