Nocturnal hypertension and organ damage in dippers and nondippers

American Journal of Hypertension
C CuspidiGiuseppe Mancia

Abstract

The relationship between high nocturnal blood pressure (BP), organ damage and the dipping/nondipping status is poorly defined. We investigated whether a consistent dipping/nondipping pattern defined on the basis of two 24-h ambulatory BP monitorings (ABPMs) is associated with subclinical organ damage in untreated hypertensive patients with elevated nighttime BP. All subjects underwent the following procedures: cardiac and carotid ultrasonography, 24-h urine collection for microalbuminuria (MA), and ABPM over two 24-h periods within 4 weeks. Nocturnal hypertension was defined according to current guidelines (i.e., nighttime systolic BP (SBP) ≥120 and/or diastolic BP ≥70 mm Hg) and nondipping status as an average reduction in SBP at night <10% compared with day-time values. Among 343 subjects, 199 were dippers and 144 nondippers. No differences were found in clinical variables, average 48-h BP, left ventricular mass, carotid intima-media (IM) and urinary albumin excretion between the groups. This was also the case for prevalence rates of left ventricular hypertrophy, carotid IM thickening or plaque and MA. Finally, no relationship was found between the markers of organ damage and BP fall at night. In the presence of nocturnal hyp...Continue Reading

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Citations

Aug 30, 2013·Journal of Human Hypertension·A Oliveras, A de la Sierra
Sep 26, 2013·American Journal of Hypertension·Alejandro de la SierraLuis M Ruilope
Mar 15, 2013·Clinical and Experimental Hypertension : CHE·Marijana TadicAleksandar Neskovic
Jun 8, 2013·Chronobiology International·Yoon-Sang OhKwang-Soo Lee
Oct 27, 2016·International Journal of Cardiology·Piotr DobrowolskiPiotr Hoffman
Feb 23, 2017·The Journal of International Medical Research·Feng WangShouling Wu
Mar 26, 2014·Clinical Endocrinology·Chiara SardellaFausto Bogazzi
Apr 17, 2015·Chest·Gerard TorresFerran Barbé
Jul 30, 2014·American Heart Journal·Oscar M P Jolobe
Feb 13, 2018·The Journal of Clinical Hypertension·Cesare CuspidiGuido Grassi
Oct 27, 2017·The Journal of Clinical Hypertension·Shikai Yu, Yi Zhang
Mar 15, 2015·Circulation Research·Giuseppe Mancia, Paolo Verdecchia
Mar 14, 2014·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Aleksander PrejbiszAndrzej Januszewicz
Feb 13, 2019·American Journal of Hypertension·Marilucy Lopez-SubletPatrick Rossignol
Apr 3, 2014·Journal of Neural Transmission·Joong-Seok KimDavid S Goldstein
Aug 17, 2019·American Journal of Hypertension·Adam MahdiLionel Tarassenko
Dec 25, 2012·Current Opinion in Ophthalmology·Ahmad A Aref
Jan 29, 2016·Journal of Hypertension·Cesare CuspidiGiuseppe Mancia
Sep 6, 2020·Journal of Hypertension·Marijana Tadic, Cesare Cuspidi
Nov 14, 2013·Journal of Hypertension·Cesare Cuspidi, Guido Grassi
Aug 18, 2017·Journal of Hypertension·Marijana TadicGiuseppe Mancia
Oct 27, 2020·Chronobiology International·Raquel Del Pozo-ValeroAlicia Rodríguez-Barbero

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