Nocturnal hypertension in high-risk mid-pregnancies predict the development of preeclampsia/eclampsia

Journal of Hypertension
Martin R SalazarHoracio A Carbajal

Abstract

The aim of this study was to test if hypertension detected by ambulatory blood pressure monitoring (ABPM) performed at mid-pregnancy, is a useful predictor for preeclampsia/eclampsia (PEEC). The study was performed in women coursing high-risk mid-pregnancies. Office blood pressure (BP) was estimated as the mean of three values, taken by a specialized nurse after a 15-min interview, and office hypertension defined as at least 140/90 mmHg. Immediately after, an ABPM was started. Diurnal hypertension was defined as ABPM at least 135/85 mmHg during daily activities, nocturnal hypertension as ABPM at least 120/70 mmHg during night rest. The adjusted risk of PEEC was estimated using logistic regression. Eighty-seven women (mean age 31 ± 7 years) with 23 ± 2 weeks of pregnancy were included. The prevalence of office and ABPM hypertension was 13.8 and 40.2%, respectively. The concordance between both hypertension diagnosis was low (κ = 0.170, P = 0.044). Nocturnal hypertension (35.6%) was more frequent than diurnal hypertension (26.4%). Nocturnal hypertension markedly increased the relative risk of PEEC (OR 5.32, 95% CI 1.48-19.10). The risk of PEEC attributed to diurnal hypertension did not reach statistical significance; and when bot...Continue Reading

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Aug 5, 2016·Journal of Hypertension·Martin R SalazarHoracio A Carbajal
Sep 30, 2016·Journal of Hypertension·Grzegorz Bilo, Gianfranco Parati
Jun 29, 2017·The New England Journal of Medicine·Daniel L RolnikKypros H Nicolaides

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Citations

Jul 10, 2019·Expert Review of Medical Devices·Asma KhalilWilfried Gyselaers
Jun 4, 2019·Journal of Hypertension·Martin R SalazarHoracio A Carbajal
Aug 25, 2020·Psychosomatic Medicine·Margaret H BublitzGhada Bourjeily
Dec 5, 2020·Zeitschrift für Geburtshilfe und Neonatologie·Werner RathDietmar Schlembach
Sep 5, 2021·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Martin R SalazarHoracio A Carbajal

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