Nocturnal supervision and SUDEP risk at different epilepsy care settings

Neurology
Marije van der LendeRoland D Thijs

Abstract

To estimate the incidence of sudden unexpected death in epilepsy (SUDEP) in people with intellectual disabilities in residential care settings and to ascertain the effects of nocturnal seizures and nocturnal supervision on SUDEP risk. We conducted a nested case-control study reviewing records of all people who died at 2 residential care settings over 25 years. Four controls per case were selected from the same population, matched on age (±5 years) and residential unit. Nocturnal supervision was graded in 3 categories: (1) no supervision; (2) a listening device or a roommate or physical checks at least every 15 minutes; and (3) 2 of the following: a listening device, roommate, additional device (bed motion sensor/video monitoring), or physical checks every 15 minutes. Outcome measures were compared using Mann-Whitney U tests and Fisher exact tests. We identified 60 SUDEP cases and 198 matched controls. People who died of SUDEP were more likely to have nocturnal convulsive seizures in general (77% of cases vs 33% of controls, p < 0.001) and a higher frequency of nocturnal convulsive seizures. Total SUDEP incidence was 3.53/1,000 patient-years (95% confidence interval [CI] 2.73-4.53). The incidence differed among centers: 2.21/1,0...Continue Reading

References

Feb 1, 1993·Journal of Neurology, Neurosurgery, and Psychiatry·P KlenermanS D Shorvon
Apr 4, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·L NashefS D Shorvon
Jan 25, 2000·Journal of Neurology, Neurosurgery, and Psychiatry·Y LanganJ W Sander
Aug 10, 2000·American Journal of Mental Retardation : AJMR·J R McKee, J W Bodfish
Apr 13, 2005·Neurology·Y LanganJ W Sander
Nov 5, 2005·Brain Research. Brain Research Reviews·J F R PatonE Nalivaiko
Jan 2, 2007·Epilepsy & Behavior : E&B·Nikolas HitirisMartin J Brodie
Nov 14, 2007·Archives of Neurology·Christian HoppeChristian E Elger
Jul 16, 2010·Epilepsy & Behavior : E&B·H ElzawahryS R Benbadis
Jun 16, 2011·Epilepsia·Dale C HesdorfferUNKNOWN ILAE Commission on Epidemiology; Subcommission on Mortality
Dec 24, 2011·Epilepsia·Dale C HesdorfferUNKNOWN ILAE Commission on Epidemiology (Subcommission on Mortality)
Dec 24, 2011·Epilepsia·Lina NashefTorbjörn Tomson
Jul 5, 2013·Brain : a Journal of Neurology·Jan NovySanjay M Sisodiya
Jun 7, 2014·Epilepsia·David J ThurmanJacqueline A French
Jan 23, 2015·Neurology·Jennifer A LiebenthalJames X Tao
Jun 4, 2015·Journal of Neurology, Neurosurgery, and Psychiatry·Marije van der LendeRoland D Thijs
Dec 18, 2015·Neurology·Orrin DevinskyDaniel Friedman
Jun 29, 2016·Epilepsy & Behavior : E&B·Shuang WangJames X Tao
Jul 20, 2016·The Cochrane Database of Systematic Reviews·Melissa J MaguireSarah J Nolan
Aug 5, 2016·Epilepsy & Behavior : E&B·Sharon ShmuelyRoland D Thijs
Aug 28, 2016·Seizure : the Journal of the British Epilepsy Association·Anouk Van de VelBerten Ceulemans
Aug 30, 2016·Lancet Neurology·Orrin DevinskyGeorge Richerson
Oct 1, 2016·Epilepsia·Marije van der LendeRoland D Thijs
Sep 18, 2017·Epilepsy & Behavior : E&B·Ahmer AliJames X Tao

❮ Previous
Next ❯

Citations

Sep 23, 2018·Neurology·Orrin DevinskyFrank M C Besag
Nov 1, 2018·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Anouk van WestrhenenRoland D Thijs
Sep 7, 2019·Herzschrittmachertherapie & Elektrophysiologie·Theodor W May, Carsten W Israel
Dec 14, 2019·Neurology·Olafur SveinssonTorbjörn Tomson
Oct 26, 2018·Neurology·Johan ArendsUNKNOWN the Dutch Tele-Epilepsy Consortium
Mar 25, 2019·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Roland D Thijs
Mar 25, 2020·Annals of Clinical and Translational Neurology·Sharon ShmuelyRoland D Thijs
Apr 3, 2020·The Cochrane Database of Systematic Reviews·Melissa J MaguireSarah J Nevitt
Apr 10, 2020·Expert Review of Neurotherapeutics·Max Christian PenselRainer Surges
May 8, 2020·Epilepsia·Anouk van WestrhenenRoland D Thijs
Jun 11, 2020·Epilepsia·Sándor BeniczkyPhilippe Ryvlin
Jan 9, 2019·Frontiers in Neurology·Benton S PurnellGordon F Buchanan
Jan 30, 2019·Current Opinion in Neurology·Philippe RyvlinSamden D Lhatoo
Jan 24, 2021·Epilepsy & Behavior : E&B·Anouk van WestrhenenRoland D Thijs
Dec 24, 2019·Experimental Neurology·Alexandra N PetrucciGordon F Buchanan
Jun 5, 2021·Epilepsia·Roozbeh Tarighati RasekhiMaromi Nei
May 25, 2021·Epilepsy Currents·Orrin Devinsky, Sanjay M Sisodiya
Jul 14, 2021·Epilepsy & Behavior : E&B·Celia GreenlawLaurie M Douglass
Jun 3, 2020·Seizure : the Journal of the British Epilepsy Association·James J SunRohit Shankar
Aug 4, 2021·Autonomic Neuroscience : Basic & Clinical·Maromi Nei, Allyson Pickard
Oct 31, 2021·Nature Reviews. Neurology·Roland D ThijsRainer Surges

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.