Nodal staging in penile carcinoma by dynamic sentinel node biopsy after previous therapeutic primary tumour resection

European Urology
Niels M GraaflandSimon Horenblas

Abstract

Dynamic sentinel node biopsy (DSNB) is used to evaluate the nodal status of patients with penile carcinoma and clinically node-negative groins. This minimally invasive procedure is usually done at the same time as the treatment of the primary tumour. Our aim was to evaluate results of so-called postresection DSNB, that is, DSNB after previous resection of the penile tumour. All 40 patients who had undergone DSNB after previous penile carcinoma resection with histopathologically tumour-negative margins between February 2003 and July 2009 were analysed. Twenty patients (50%) had known unilateral nodal involvement, and DSNB was used to stage the clinically normal contralateral groin. Hence the study concerned 60 groins without palpable nodes. The median time between primary tumour resection and DSNB was 2.8 mo. The technique of postresection DSNB was similar to the standard procedure. The sentinel node visualisation rate, identification rate, histopathologic results, and outcome during follow-up were investigated. A sentinel node was visualised on the lymphoscintigrams of 56 of the 60 eligible groins (93%). A sentinel node was identified intraoperatively in all these 56 groins. A median of two sentinel nodes were removed. Histopat...Continue Reading

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Citations

Apr 11, 2013·Der Urologe. Ausg. A·J FuchsC M Naumann
Jan 30, 2013·Chinese Journal of Cancer Research = Chung-kuo Yen Cheng Yen Chiu·Yao Zhu, Ding-Wei Ye
Jan 8, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·G SonpavdeG Di Lorenzo
May 24, 2011·Advances in Urology·Maria Carmen MirNathan Lawrentschuk
Nov 3, 2011·The Urologic Clinics of North America·Victoria Chernyak
Oct 16, 2016·Clinical and Translational Imaging : Reviews in Nuclear Medicine and Molecular Imaging·O R BrouwerS Horenblas
Nov 18, 2016·Der Urologe. Ausg. A·H G van der PoelS Horenblas
Jul 28, 2019·Biomedizinische Technik. Biomedical Engineering·Ali Pashazadeh, Michael Friebe
Feb 9, 2017·European Journal of Nuclear Medicine and Molecular Imaging·Ziauddin Zia SaadJamshed Bomanji

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