NodFE-dependent fatty acids that lack an alpha-beta unsaturation are subject to differential transfer, leading to novel phospholipids

Molecular Plant-microbe Interactions : MPMI
Otto GeigerJ E Thomas-Oates

Abstract

In Rhizobium leguminosarum, the nodABC and nodFEL operons are involved in the production of lipo-chitin oligosaccharide signals that mediate host specificity. A nodFE-determined, highly unsaturated C18:4 fatty acid (trans-2, trans-4, trans-6, cis-11-octadecatetraenoic acid) is essential for the ability of the signals to induce nodule meristems and pre-infection thread structures on the host plant Vicia sativa. Of the nod genes, induction of only nodFE is sufficient to modify fatty acid biosynthesis to yield trans-2, trans-4, trans-6, cis-11-octadecatetraenoic acid, with an absorbance maximum of 303 nm. This unusual C18:4 fatty acid is not only found in the lipo-chitin oligosaccharides but is also associated with the phospholipids (O. Geiger, J. E. Thomas-Oates, J. Glushka, H. P. Spaink, and B. J. J. Lugtenberg, 1994, J. Biol. Chem. 269:11090-11097). Here we report that the phospholipids can contain other nodFE-derived fatty acids, a C18:3 trans-4, trans-6, cis-11-octadecatrienoic acid that has a characteristic absorption maximum at 225 nm, and a C18:2 octadecadienoic acid. Neither this C18:3 nor this C18:2 fatty acid has to date been observed attached to lipo-chitin oligosaccharides, suggesting that an as yet unknown acyl trans...Continue Reading

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Citations

Mar 14, 2003·Biochimica Et Biophysica Acta·Adam Choma, Iwona Komaniecka
Mar 30, 2001·Molecular Plant-microbe Interactions : MPMI·I M López-Lara, O Geiger
Nov 8, 2002·Systematic and Applied Microbiology·Adam Choma, Iwona Komaniecka
Oct 6, 2000·Annual Review of Microbiology·H P Spaink
Aug 31, 1999·Carbohydrate Research·N P Price

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