Nodular glomerulosclerosis in patients' without history of diabetes mellitus: a case report.

Cases Journal
Imed HelalAdel Kheder

Abstract

Diabetic nephropathy can occur during the course of both type1 and type 2 diabetes mellitus. The characteristic lesions are diffuse or nodular (Kimmelsteil-Wilson) diabetic glomerulosclerosis. The reported cases represent unusual presentations of diabetes mellitus. We report the case of a 49-year-old man without prior history of diabetes mellitus who presented with rapidly progressive renal failure and whose renal biopsy revealed nodular (Kimmelsteil-Wilson) glomerulosclerosis lesions characteristic of diabetes. Renal manifestations of diabetes mellitus may antedate other more common presenting symptoms of this disease and we critically review the literature on this subject.

References

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Apr 1, 1992·Kidney International·H H ParvingS Larsen
Dec 1, 1996·Diabetologia·P FiorettoR Nosadini
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Mar 1, 2003·Diabetes Care·Paul HoganUNKNOWN American Diabetes Association
Jun 6, 2003·The New England Journal of Medicine·Bruce A PerkinsAndrzej S Krolewski
Feb 26, 2008·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Emilie CounilHichem Trimech

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Citations

Aug 19, 2011·Clinical and Experimental Nephrology·Chiharu KinoshitaChiaki Kanda
Aug 5, 2015·Journal of Clinical Medicine·Katia López-RevueltaElia Pérez Fernández

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Methods Mentioned

BETA
electrophoresis
urine collection
biopsy

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