PMID: 11917223Mar 28, 2002Paper

Nodular histiocytic hyperplasia of the endometrium

International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists
Kyu-Rae KimJae Y Ro

Abstract

We describe the clinical and pathologic features of four cases of nodular histiocytic proliferation in the endometrium. We have been able to find only one brief reference to this lesion in the literature. The lesion in each case was a detached nodule composed of aggregates of histiocytes within a biopsy or curettage specimen. The constituent cells differed from foamy histiocytes of the endometrium in that they had either lobulated or ovoid, vesicular nuclei, distinctive cytoplasmic margins, and a moderate amount of amphophilic cytoplasm. Mitoses were frequent (up to 11 per 10 high-power fields) in one case but were absent in the remaining cases. On immunohistochemical staining, CD68 and lysozyme were strongly expressed in the cytoplasm. Neither estrogen receptor nor progesterone receptor was expressed in contrast to the background endometrium. The cells were also negative for S-100 and cytokeratin. Each patient's postcurettage course was uneventful. The cause of nodular histiocytic proliferation of the endometrium is currently unknown, although response to intracavitary debris has been suggested. The lesion should not be confused with a variety of reactive, inflammatory, or neoplastic conditions, such as xanthogranulomatous end...Continue Reading

References

Mar 15, 1991·Cancer·C A AxiotisP H Duray
Feb 1, 1991·Histopathology·M ShintakuY Baba
May 1, 1988·Histopathology·K C WongJ K Chan
Nov 1, 1988·Histopathology·C Ladefoged, M Lorentzen
Jan 1, 1972·American Journal of Obstetrics and Gynecology·N N Budny
Nov 1, 1983·American Journal of Clinical Pathology·J J Molnar, A Poliak
Jan 1, 1983·Acta Obstetricia Et Gynecologica Scandinavica·M AshkenazyB Czernobilsky
Feb 1, 1982·Gynecologic Oncology·M P Dawagne, S G Silverberg
Jun 1, 1995·American Journal of Clinical Pathology·P B Clement
May 15, 1998·The American Journal of Surgical Pathology·N G OrdóñezA G Ayala

❮ Previous
Next ❯

Citations

May 13, 2008·Archives of Gynecology and Obstetrics·Eleni KarvouniAgatha Kondi-Paphiti
Feb 10, 2012·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Michael A Dimaio, Teri A Longacre
Dec 5, 2013·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Vinita ParkashOluwole Fadare
Apr 14, 2012·Indian Journal of Pathology & Microbiology·Seema RaoAnup Mohta
Apr 30, 2014·Lung India : Official Organ of Indian Chest Society·Seema RaoArvind Kumar
May 27, 2006·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Frank NoackHans-Peter Horny
Sep 15, 2016·The New England Journal of Medicine·Richard S LegroDrucilla J Roberts
Oct 9, 2015·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Colin J R Stewart, Robyn Leake
Aug 30, 2013·The American Journal of Case Reports·Jyotsna V WaderVaishali Vhawal
Sep 1, 2004·Archives of Pathology & Laboratory Medicine·Masaharu Fukunaga, Satoko Iwaki

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacterial Cell Wall Structure

Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Here is the latest research on bacterial cell wall structures.

Bacterial Cell Wall Structure (ASM)

Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Here is the latest research on bacterial cell wall structures.