PMID: 9557777Apr 29, 1998Paper

Nodular melanosis due to epithelial neoplasms: a finding not restricted to regressed melanomas

The American Journal of Dermatopathology
S H FlaxG P Lupton

Abstract

Nodular or tumoral melanosis consists of nodular or sheetlike deposits of melanophages in the dermis. When nodular melanosis is present, a completely regressed malignant melanoma is a major diagnostic consideration. We present a case of nodular melanosis due to regression of a pigmented basal cell carcinoma with pilar differentiation. In addition to this case, we present five additional cases of epithelial neoplasms with melanin deposition in the stroma. In each case, the source of the melanin was non-neoplastic dendritic melanocytes intermingled among the tumor cells. Therefore, if nodular melanosis is found, pigmented epithelial neoplasms should also be considered in the differential diagnosis.

References

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Citations

May 2, 2009·Brain Tumor Pathology·Hitoshi TsuguKoichi Takano
Jan 27, 2009·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Jean-Pierre A MartelRichard N Rankin
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Mar 16, 2017·The American Journal of Dermatopathology·Robert L Grohs, Nima Mesbah Ardakani
Jul 27, 2007·Virchows Archiv : an International Journal of Pathology·Guido Massi
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Nov 28, 2013·Pediatric Dermatology·Seval Dogruk KacarFatma Aktepe
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Dec 20, 2011·Histopathology·Thomas Brenn
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Sep 15, 2011·International Journal of Dermatology·Elisabeth RoiderCarola Berking
Apr 23, 2019·The American Journal of Dermatopathology·Andrea SagginiLorenzo Cerroni
Dec 17, 2014·Journal of the European Academy of Dermatology and Venereology : JEADV·G Solano-LópezE Daudén
Feb 9, 2020·International Journal of Pediatric Otorhinolaryngology·Elizabeth F BoscoePeggy Kelley
Aug 6, 2009·Archives of Pathology & Laboratory Medicine·Patrick Malafronte, Timothy Sorrells

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