Noise-induced tuning curve changes in mechanoreceptors

Journal of Neurophysiology
C IveyD R Chialvo

Abstract

Fibers from the tibial nerve of rat were isolated and spike activity recorded using monopolar hook electrodes. The receptive field (RF) of each recorded unit on the glabrous skin of the foot was mechanically stimulated with waveforms comprised of various frequency sine waves in addition to increasing levels of white noise. Single-unit responses were recorded for both rapidly adapting (RA) and slowly adapting (SA) units. Signal-to-noise ratio (SNR) of the output was quantified by the correlation coefficient (C1) between the input sine wave and the nerve responses. The addition of noise enhanced signal transmission in both RA and SA fibers. With increasing noise, the initially inverted "V"-shaped, zero-noise tuning curves for RA fibers broadened and eventually inverted. There was a large expansion of the frequencies that the RA receptor responded to with increasing noise input. On the other hand, the typical shape of the SA fiber tuning curves remained invariant, at all noise levels tested. C1 values continued to increase with larger noise input for higher frequencies, but did not do so at the lowest frequencies. For both RA and SA fibers the responses with added noise tended to be rate modulated at the low-frequency end, and fol...Continue Reading

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Citations

Dec 17, 2003·Somatosensory & Motor Research·Burak Güçlü, Stanley J Bolanowski
Jun 21, 2011·Nature Reviews. Neuroscience·Mark D McDonnell, Lawrence M Ward
Sep 9, 2015·Frontiers in Systems Neuroscience·Ajitkumar P MulavaraJacob J Bloomberg
Jun 24, 2018·Science China. Life Sciences·Luyuan JinSonglin Wang
Jan 23, 2004·Journal of Neurophysiology·James B FallonDavid L Morgan
Mar 25, 2005·Journal of Neurophysiology·James B Fallon, David L Morgan
May 29, 2013·Experimental Brain Research·Edith Ribot-CiscarJean-Marc Aimonetti
Nov 16, 2005·Annals of Neurology·Attila A PriplataJames J Collins
Mar 29, 2011·Experimental Brain Research·Ajitkumar P MulavaraJacob J Bloomberg
Oct 21, 2014·PloS One·Agustín L Herrera-MayElias Manjarrez
Jun 13, 2002·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Dante R ChialvoGuillermo V Savino
Nov 3, 2001·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·S Tanabe, K Pakdaman
Apr 20, 2001·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·S Tanabe, K Pakdaman
May 1, 2001·Physical Review Letters·M Rudolph, A Destexhe
Dec 12, 2001·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·K Pakdaman, S Tanabe

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