Noise reduction in dual-energy computed tomography virtual monoenergetic imaging

Journal of Applied Clinical Medical Physics
Chi-Kuang Liu, Hsuan-Ming Huang

Abstract

Virtual monoenergetic images (VMIs) derived from dual-energy computed tomography (DECT) have been explored for several clinical applications in recent years. However, VMIs at low and high keVs have high levels of noise. The aim of this study was to reduce image noise in VMIs by using a two-step noise reduction technique. VMI was first denoised using a modified highly constrained backprojection (HYPR) method. After the first-step denoising, a general-threshold filtering method was performed. Two sets of anthropomorphic phantoms were scanned with a clinical dual-source DECT system. DECT data (80/140Sn kV) were reconstructed as VMI series at 12 different energy levels (range, 40-150 keV, interval, 10 keV). For comparison, the averaged VMIs obtained from 10 repeated DECT scans were used as the reference standard. The signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and root-mean-square error (RMSE) were used to evaluate the quality of VMIs. Compared to the original HYPR method, the proposed two-step image denoising method could provide better performance in terms of SNR, CNR, and RMSE. In addition, the proposed method could achieve effective noise reduction while preserving edges and small structures, especially for low-k...Continue Reading

References

Dec 13, 2005·European Radiology·Thomas G FlohrBernd M Ohnesorge
Dec 13, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·C A MistrettaY Wu
Dec 8, 2006·European Radiology·Thorsten R C JohnsonChristoph R Becker
Nov 24, 2007·Academic Radiology·Andrew N PrimakCynthia H McCollough
Feb 29, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Kevin M JohnsonCharles A Mistretta
Aug 28, 2010·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Mitsuru IkedaRika Hitomi
Jan 21, 2011·European Radiology·Fabian BambergThorsten R C Johnson
Jun 10, 2011·Physics in Medicine and Biology·Adriënne M MendrikMathias Prokop
Nov 10, 2011·Current Urology Reports·Jong ParkAlec J Megibow
Nov 1, 2012·AJR. American Journal of Roentgenology·Thomas HenzlerU Joseph Schoepf
Nov 1, 2012·AJR. American Journal of Roentgenology·Lifeng YuCynthia H McCollough
Mar 14, 2014·Physiological Measurement·Jung-Hui LiHsuan-Ming Huang
Apr 4, 2014·Medical Physics·Tianye NiuLei Zhu
May 8, 2014·IEEE Transactions on Medical Imaging·Yong Long, Jeffrey A Fessler
Aug 19, 2015·IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society·Chuang Miao, Hengyong Yu
Oct 16, 2015·Journal of Computer Assisted Tomography·Moritz KaupJulian L Wichmann
Jan 10, 2016·Medical Physics·Zhoubo LiCynthia H McCollough
Aug 10, 2018·Physics in Medicine and Biology·Chieh LinHsuan-Ming Huang

❮ Previous
Next ❯

Software Mentioned

HYPR
DECT
Syngo VE
Monoenergetic Application Class

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.