Non-antibiotic medication use in an Indonesian community cohort 0-18 months of age

PloS One
Jarir At ThobariJulie E Bines

Abstract

Rational medication use for treatment is mandatory, particularly in children as they are vulnerable to possible hazards of drugs. Understanding the medication use pattern is of importance to identify the problems of drug therapy and to improve the appropriate use of medication among this population. A post-hoc study of the RV3-BB Phase IIb trial to children aged 0-18 months which was conducted in Indonesia during January 2013 to July 2016. Any concomitant medication use and health events among 1621 trial participants during the 18 months of follow-up were documented. Information on medication use included the frequency, formulation, indication, duration of usage, number of regimens, medication types, and therapeutic classes. The majority of participants (N = 1333/1621; 82.2%) used at least one non-antibiotic medication for treatment during the 18-month observation period. A total of 7586 medication uses were recorded, mostly in oral formulation (90.5%). Of all illnesses recorded, 24.7% were treated with a single drug regimen of non-antibiotic medication. The most common therapeutic classes used were analgesics/antipyretics (30.1%), antihistamines for systemic use (17.4%), cough and cold preparations (13.5%), vitamins (8.6%), an...Continue Reading

References

Jun 1, 1989·Journal of Epidemiology and Community Health·F Rasmussen, B Smedby
Jul 1, 1987·Acta Neurologica Scandinavica·K Dalton, M J Dalton
Nov 9, 2000·British Journal of Clinical Pharmacology·E SchirmL De Jong-van den Berg
Mar 10, 2001·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·A P Ten EickM D Reed
Jan 5, 2002·European Journal of Clinical Pharmacology·T CazzatoUNKNOWN ACP Puglia-Basilicata Working Group
May 4, 2006·British Journal of Clinical Pharmacology·Iftekhar Mahmood
Oct 26, 2006·Acta Paediatrica·Birgit V-L Niclasen
Jan 30, 2008·Pediatrics·Melissa K SchaeferDaniel S Budnitz
May 1, 2008·European Journal of Pediatrics·Antonio ClavennaMaurizio Bonati
Aug 5, 2008·Pediatrics·Mary E Rimsza, Susan Newberry
Nov 26, 2008·BMJ : British Medical Journal·Miriam C J M SturkenboomUNKNOWN TEDDY European Network of Excellence
Dec 23, 2008·Annals of Emergency Medicine·Richard C DartBarry H Rumack
Jul 8, 2010·Indian Journal of Community Medicine : Official Publication of Indian Association of Preventive & Social Medicine·Anuja A PandeyPrakash R Bhatkule
Jun 24, 2014·Jornal de pediatria·Maria J B CruzDelba F Santos
Oct 3, 2014·Perspectives in Clinical Research·Nimbagiri Swamy ThiruthopuSrinivas Martha
Nov 6, 2014·British Journal of Clinical Pharmacology·Albert Ferro
Mar 4, 2015·Ethiopian Journal of Health Sciences·Joseph FadareOlatunde Ogundare
Apr 10, 2015·British Journal of Clinical Pharmacology·Hannah Katharine Batchelor, John Francis Marriott
Jul 3, 2015·Pediatrics in Review·Jennifer A Lowry, J Steven Leeder
Dec 23, 2015·Drugs -- Real World Outcomes·Asia N RashedAntje Neubert
Mar 17, 2016·Archives of Disease in Childhood·Diana A van Riet-NalesCarin M A Rademaker
Jan 8, 2017·Inflammopharmacology·Dipak J Kanabar
Feb 22, 2018·The New England Journal of Medicine·Julie E BinesYati Soenarto
Nov 23, 2018·European Journal of Clinical Pharmacology·Philippe VorilhonAurélie Cabaillot
Aug 6, 2019·PloS One·Jarir At ThobariJim P Buttery

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.