Non-arteritic anterior ischemic optic neuropathy (NA-AION) after intravitreal injection of bevacizumab (Avastin) for treatment of angoid streaks in pseudoxanthoma elasticum.

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Martin GanssaugeSabine Aisenbrey

Abstract

To report a case of nonarteritic anterior ischemic optic neuropathy (NA-AION) following intravitreal injection of bevacizumab (Avastin). Interventional case report with an 18-month follow-up. A 51-year-old male with pseudoxanthoma elasticum presented with NA-AION 2 weeks after treatment with intravitreal of bevazicumab (Avastin) for choroidal neovascularisation secondary to angioid streaks. Except from a small optic disc without cupping he did not show further risk factors. Risk of NA-AION should be taken into consideration when deciding for intravitreal application of drugs including anti-vascular endothelial growth factors (VEGF) agents like bevacizumab (Avastin) in the treatment of retinal vascular diseases.

References

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Citations

Nov 17, 2009·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Sohan Singh Hayreh
Jun 26, 2010·Japanese Journal of Ophthalmology·Jane Y HuangEiichi Uchio
Feb 26, 2011·Indian Journal of Ophthalmology·Sohan Singh Hayreh
Sep 3, 2011·Middle East African Journal of Ophthalmology·Hassan Al-Dhibi, Arif O Khan
Aug 17, 2010·Survey of Ophthalmology·Kathryn L PeppleRod Foroozan
Dec 28, 2017·Middle East African Journal of Ophthalmology·T LekhaS Karthikeyan
Apr 25, 2015·European Journal of Ophthalmology·Nurgül ÖrnekKemal Örnek

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