PMID: 6164616Jan 1, 1981Paper

Non-blastic meningeal leukemia during the myelofibrotic phase of chronic myeloid leukemia

Folia haematologica : internationales Magazin für klinische und morphologische Blutforschung
P AversaM F Martelli

Abstract

Myeloblastic involvement of the central nervous system has been noted in the course of chronic myeloid leukemia in the blastic phase; meningeal leukemia in the chronic phase of CML is almost unknown. We report on a case of CML in which meningeal infiltration by cells of the granulocytes series in all stage of cellular maturation developed 15 years after initial diagnosis and seven months after a myelofibrotic transformation of the systemic disease.

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