Non-cooperative oxygen binding in the erythrocytes of pre-implanted sheep embryos

Comparative Biochemistry and Physiology. A, Comparative Physiology
R M Wells, T Brittain


The whole-blood oxygen equilibrium curve in sheep embryos at 17 days gestation was essentially hyperbolic, indicating non-cooperative O2 binding with Hill's coefficient, n approximately equal to 1.2. O2 affinity was higher in embryonic blood (P50 = 7.1 mmHg at pH = 7.4 and 39 degrees C) than in maternal blood (P50 = 32.6 mmHg at pH = 7.4 and 39 degrees C). The Bohr effect was apparently smaller in the embryo (delta log P50/delta pH = --0.52) than in maternal blood (--0.36).


Jul 1, 1975·New Zealand Veterinary Journal·G V Wallace
Nov 29, 1974·Annals of the New York Academy of Sciences·H Kitchen, I Brett
Nov 29, 1974·Annals of the New York Academy of Sciences·B HammerbergH Kitchen

Related Concepts

AT 17
Entire Embryo
Dall Sheep
Gestational Age
Oxygen Binding Activity
Sheep antigen
Specimen Type - Erythrocytes
Domestic Sheep

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