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Non-crossover gene conversions show strong GC bias and unexpected clustering in humans

ELife

Mar 26, 2015

Amy L WilliamsT2D-GENES Consortium

Abstract

Although the past decade has seen tremendous progress in our understanding of fine-scale recombination, little is known about non-crossover (NCO) gene conversion. We report the first genome-wide study of NCO events in humans. Using SNP array data from 98 meioses, we identified 103 sites...read more

Mentioned in this Paper

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Zinc Fingers
Genome-Wide Association Study
Meiotic Cell Cycle
Abnormal Degeneration
Genome
Genes
Malignant Neoplasm of Stomach
Tract
Segmental Duplications, Genomic
16
1
98
Paper Details
References
  • References49
  • Citations27
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  • References49
  • Citations27
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Non-crossover gene conversions show strong GC bias and unexpected clustering in humans

ELife

Mar 26, 2015

Amy L WilliamsT2D-GENES Consortium

PMID: 25806687

DOI: 10.7554/elife.04637

Abstract

Although the past decade has seen tremendous progress in our understanding of fine-scale recombination, little is known about non-crossover (NCO) gene conversion. We report the first genome-wide study of NCO events in humans. Using SNP array data from 98 meioses, we identified 103 sites...read more

Mentioned in this Paper

Establishment and Maintenance of Localization
Zinc Fingers
Genome-Wide Association Study
Meiotic Cell Cycle
Abnormal Degeneration
Genome
Genes
Malignant Neoplasm of Stomach
Tract
Segmental Duplications, Genomic
16
1
98

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Nature

High-resolution mapping of meiotic crossovers and non-crossovers in yeast

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Paper Details
References
  • References49
  • Citations27
12345
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  • Citations27
123
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