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Non-crossover gene conversions show strong GC bias and unexpected clustering in humans

ELife

Mar 25, 2015

Amy L. WilliamsT2D-GENES Consortium

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Abstract

Although the past decade has seen tremendous progress in our understanding of fine-scale recombination, little is known about non-crossover (NCO) gene conversion. We report the first genome-wide study of NCO events in humans. Using SNP array data from 98 meioses, we identified 103 sites...read more

Mentioned in this Paper

Synapses
Homologous Gene
Oligonucleotide Primers
Dideoxy Chain Termination DNA Sequencing
Weighing Patient
Single Nucleotide Polymorphism Database
Single Nucleotide Polymorphism
Synapsis genus
Biologic Degeneration
Establishment and Maintenance of Localization
15
1
96
Paper Details
References
    • References49
    • Citations20
    • References49
    • Citations20
  • Non-crossover gene conversions show strong GC bias and unexpected clustering in humans

    ELife

    Mar 25, 2015

    Amy L. WilliamsT2D-GENES Consortium

    PMID: 25806687

    DOI: 10.7554/elife.04637

    Abstract

    Although the past decade has seen tremendous progress in our understanding of fine-scale recombination, little is known about non-crossover (NCO) gene conversion. We report the first genome-wide study of NCO events in humans. Using SNP array data from 98 meioses, we identified 103 sites...read more

    Mentioned in this Paper

    Synapses
    Homologous Gene
    Oligonucleotide Primers
    Dideoxy Chain Termination DNA Sequencing
    Weighing Patient
    15
    1
    96

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    Paper Details
    References
    • References49
    • Citations20
    • References49
    • Citations20
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