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Non-crossover gene conversions show strong GC bias and unexpected clustering in humans

bioRxiv

Sep 16, 2014

Amy L. Williams

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Abstract

Although the past decade has seen tremendous progress in our understanding of fine-scale recombination, little is known about non-crossover (NCO) gene conversion. We report the first genome-wide study of NCO events in humans. Using SNP array data from 98 meioses, we identified 103 sites...read more

Mentioned in this Paper

Single Nucleotide Polymorphism
Genome-Wide Association Study
Site
Genes
Malignant Neoplasm of Stomach
Recombination, Genetic
Meiosis
DNA Resequencing
Alleles
Research Design
22
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  • Non-crossover gene conversions show strong GC bias and unexpected clustering in humans

    bioRxiv

    Sep 16, 2014

    Amy L. Williams

    PMID: 990009175

    DOI: 10.1101/009175

    Abstract

    Although the past decade has seen tremendous progress in our understanding of fine-scale recombination, little is known about non-crossover (NCO) gene conversion. We report the first genome-wide study of NCO events in humans. Using SNP array data from 98 meioses, we identified 103 sites...read more

    Mentioned in this Paper

    Single Nucleotide Polymorphism
    Genome-Wide Association Study
    Site
    Genes
    Malignant Neoplasm of Stomach
    22

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