Non-edible Oil Cakes as a Novel Substrate for DPA Production and Augmenting Biocontrol Activity of Paecilomyces variotii

Frontiers in Microbiology
Kalpana AroraAshwani Kumar

Abstract

The present study investigated the use of waste non-edible oil cakes (Jatropha, Karanja, Neem, and Mahua) as a substrate for the growth of Paecilomyces variotii and dipicolinic acid (DPA) production. Previous researches proved the efficacy of DPA in suppressing certain pathogens that are deleterious to the plants in the rhizosphere. DPA production was statistical optimized by amending non-edible oil cakes in growing media as nitrogen and sugars (Dextrose, Glucose, and Lactose) as carbon source. Plackett-Burman design (PBD), indicated that Jatropha cake, Karanja cake, and Dextrose were the most significant components (p < 0.05) of the media and were further optimized using response surface methodology (RSM). Jatropha cake, Karanja cake, and Dextrose at the concentration of 12.5, 4.5, and 10 g/l, respectively, yielded 250 mg/l of DPA, which was 2.5 fold more than that obtained from basal medium. HPLC analysis of the optimized medium (peak at retention time of 30 min) confirmed the enhanced DPA production by P. variotii. The scanning electron microscopy (SEM) images showed that optimized medium impose a stress like condition (due to less C:N ratio) for the fungus and generated more spores as compared to the basal medium in which c...Continue Reading

References

Aug 1, 1995·Applied Microbiology and Biotechnology·J L MilnerJ Handelsman
Feb 8, 2005·Applied Microbiology and Biotechnology·Ali AsaffMayra de la Torre
Oct 7, 2006·Bioresource Technology·Sumitra RamachandranAshok Pandey
Sep 30, 2010·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Rashad A Al-SalahiAbd El-Galil E Amr

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Citations

Aug 10, 2020·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Monika JangirSatyawati Sharma
Jun 3, 2021·Journal of Fungi·Alejandro Moreno-GavíraMila Santos

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Methods Mentioned

BETA
Thin Layer Chromatography

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