Non-functional malignant paraganglioma of the stomach

Virchows Archiv. A, Pathological Anatomy and Histopathology
C SchmidF Waltner

Abstract

We report the second case of a malignant paraganglioma of the stomach in a 56-year-old female patient. However, our case is the first investigated by immunohistochemistry and electron-microscopy. The tumour was characterized immunohistochemically by the presence of neurofilament protein, glial fibrillary acidic protein, S-100 protein, neuron-specific enolase, chromogranin A, ACTH, leu-enkephalin and vasoactive intestinal polypeptide, and ultrastructurally by demonstration of neurosecretory granules and paranuclear intermediate filament whorls. Despite massive metastatic spread in the abdominal cavity, the patient is still alive 4 years after initial diagnosis.

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Citations

Jan 1, 1992·Virchows Archiv. A, Pathological Anatomy and Histopathology·A BehamH Pickel
Dec 7, 2013·World Journal of Gastroenterology : WJG·Lin Yu, Jian Wang
Sep 5, 2009·Acta neurochirurgica·Asdrubal FalavignaAlisson R Teles
Jun 15, 2011·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Manish K KasliwalRana Patir
Jul 3, 2004·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·K HarriesJ McK Manson
Mar 19, 2011·Diagnostic Cytopathology·Juan B LaforgaNuria Juanpere
Feb 1, 1996·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·J FruhwirthJ Kainz
Oct 3, 2002·Oncogene·Clémence MagnardNicole Dalla Venezia
Apr 1, 1994·Pathology International·T FukudaT Hirono
Oct 9, 2020·Medicine·Yen-Chun HuangWen-Liang Fang

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