Non-Hodgkin lymphoma risk in adults living with HIV across five continents

AIDS
AIDS-defining Cancer Project Working Group of IeDEA, COHERE in EuroCoord

Abstract

To compare non-Hodgkin lymphoma (NHL) incidence rates in adults who started antiretroviral therapy (ART) across the Asia-Pacific, South Africa, Europe, Latin, and North America. We included cohort data of adults living with HIV who started ART after 1995 within the framework of the International epidemiology Databases to Evaluate AIDS (IeDEA) and the Collaboration of Observational HIV Epidemiological Research in Europe (COHERE). We used flexible parametric survival models to compare regional NHL rates at 2 years after ART start and to identify risk factors for NHL. We included 210 898 adults with 1.1 million person-years (pys) of follow-up and 1552 incident NHL cases (raw overall incidence rate 142/100 000 pys). After adjusting for age at ART start, first-line ART regimen, calendar period of ART start, and especially current CD4 cell count, NHL rates were similar across regions for most population groups. However, South African women remained at increased risk of developing NHL compared with their European counterparts [adjusted hazard ratio [aHR] 1.79, 95% CI 1.19-2.70]. In Europe, Latin, and North America, NHL risk was highest in MSM (aHR 1.30, 95% CI 1.14-1.48), followed by heterosexual men (referent), and women (aHR 0.66, 9...Continue Reading

References

Mar 17, 2005·Journal of the National Cancer Institute·Gary M CliffordUNKNOWN Swiss HIV Cohort
Aug 18, 2005·International Journal of Cancer. Journal International Du Cancer·Sam M MbulaiteyeEric A Engels
Feb 10, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Fabrice BonnetUNKNOWN Mortavic Study Group
May 30, 2009·The Journal of Infectious Diseases·Alexander ZoufalyUNKNOWN ClinSurv Study Group
Oct 13, 2009·The Lancet Oncology·Marguerite GuiguetUNKNOWN Clinical Epidemiology Group of the FHDH-ANRS CO4 cohort
Dec 25, 2009·Antiviral Therapy·UNKNOWN Collaboration of Observational HIV Epidemiological Research Europe (COHERE) Study GroupMatthias Egger
Jul 1, 2010·British Journal of Cancer·S FranceschiUNKNOWN Swiss HIV Cohort Study
Jan 18, 2011·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Valeria I FinkUNKNOWN Caribbean Central South America Network for HIV Research Collaboration of the International Epidemiologic Databases to Evalu
Nov 24, 2011·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Michael J SilverbergDonald I Abrams
Jun 22, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lynn E TaylorKenneth H Mayer
Sep 1, 2012·HIV Medicine·K PetoumenosUNKNOWN Australian HIV Observational Database
Jun 6, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Elizabeth L YanikJoseph J Eron
Aug 1, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Mira HleyhelUNKNOWN French Hospital Database on HIV–ANRS CO4 Cohort
Jan 10, 2014·AIDS·Paul G RubinsteinAndrew Zloza
Feb 14, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Chad J AchenbachUNKNOWN Centers for AIDS Research (CFAR) Network of Integrated Clinical Systems (CNICS)
Apr 24, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Satish GopalJoseph J Eron
Jun 6, 2014·AIDS·Philippe MorlatUNKNOWN ANRS EN20 Mortalité 2010 Study Group
Jul 16, 2015·International Journal of Cancer. Journal International Du Cancer·Eliane RohnerJulia Bohlius
Oct 6, 2015·Annals of Internal Medicine·Michael J SilverbergUNKNOWN North American AIDS Cohort Collaboration on Research and Design of the International Epidemiologic Databases to Evaluate AID
Apr 22, 2016·International Journal of Cancer. Journal International Du Cancer·Mazvita SengayiJulia Bohlius
Aug 11, 2016·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Elizabeth L YanikEric A Engels
Oct 18, 2016·Annals of Internal Medicine·Qing WangUNKNOWN Hepatitis Coinfection and Non Hodgkin Lymphoma project team for the Collaboration of Observational HIV Epidemiological Resea
Mar 16, 2017·AIDS Research and Therapy·Paul BuyegoRosalind Parkes-Ratanshi
Jun 14, 2017·AIDS·Priscila H GonçalvesRobert Yarchoan
Oct 12, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Eric A EngelsUNKNOWN North American AIDS Cohort Collaboration on Research and Design of the International Epidemiologic Datab
Dec 22, 2017·Journal of the National Cancer Institute·Leah ShepherdAmanda Mocroft
Jan 27, 2018·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·UNKNOWN IeDEA and COHERE Cohort Collaborations

❮ Previous
Next ❯

Citations

May 14, 2019·Expert Opinion on Pharmacotherapy·Vincenzo SpagnuoloAntonella Castagna
Dec 12, 2018·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Awachana JiamsakulWingwai Wong
Oct 11, 2020·Cancer Treatment and Research Communications·Alex MremiJohn Bartlett
Aug 7, 2021·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Tracey WiggillJenifer Vaughan

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.

Related Papers

AIDS
AIDS-defining Cancer Project Working Group of IeDEA and COHERE in EuroCoord
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
AIDS-defining Cancer Project Working Group for IeDEA and COHERE in EuroCoord
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Pediatric AIDS-Defining Cancer Project Working Group for IeDEA Southern Africa, TApHOD, and COHERE in EuroCoordJulia Bohlius
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Cancer Project Working Group for the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) study in Eu
© 2022 Meta ULC. All rights reserved