Non-hormonal Treatments For Menopausal Symptoms and Sleep Disturbances: A Comparison Between Purified Pollen Extracts and Soy Isoflavones.

Current Pharmaceutical Design
Pasquale De FranciscisNicola Colacurci

Abstract

Besides hot-flushes, sleep disturbances increase around menopause, impacting on the quality of life. When hormone replacement therapy is contraindicated, it is necessary to provide alternative treatments. This study aimed to observe the effects of an herbal remedy from pollen extracts and soy isoflavones for menopausal complaints, particularly on sleep disorders. A six-month prospective observational study was performed in women in natural menopause suffering from menopausal symptoms and sleep disturbances. Three groups were compared: 57 women receiving two tablets/ day containing herbal remedy from pollen extracts (group A), 60 women receiving one tablet/day containing isoflavones 60 mg (group B), 47 women not receiving any treatment (group C). At 3 (T3) and 6 months (T6), the daily number of hot-flushes, Kupperman index for menopausal symptoms, the Pittsburgh Sleep Quality Index (PSQI) test were assessed. Both groups A and B showed a significant improvement of hot flushes (p<0.001) and Kuppermann Index (p<0.001) from T0 to T3 and from T0 to T6. No significant differences between treatment groups were found at T3, while at T6 group A showed greater decrease of daily hot flashes and better improvement of Kupperman Index as comp...Continue Reading

References

Apr 1, 1995·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·E ErikssonC Sundblad
Jun 28, 2006·Archives of Internal Medicine·Maurice M Ohayon
Jun 19, 2007·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·P De FranciscisN Colacurci
Aug 19, 2011·Climacteric : the Journal of the International Menopause Society·D F ArcherM Warren
Feb 1, 2012·Internal Medicine Journal·D AmeratungaM Hickey
Feb 16, 2012·Menopause : the Journal of the North American Menopause Society·Ann-Cathrin Hellström, Jonas Muntzing
Dec 1, 2012·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Nicola ColacurciClaudio Benvenuti
Jan 17, 2013·Menopause : the Journal of the North American Menopause Society·Laura LampioPäivi Polo-Kantola
Sep 10, 2013·The Journal of Steroid Biochemistry and Molecular Biology·Robert R Freedman
May 8, 2014·Menopause : the Journal of the North American Menopause Society·Qunyan Xu, Cathryne P Lang
Jun 27, 2017·Menopause : the Journal of the North American Menopause Society·UNKNOWN The NAMS 2017 Hormone Therapy Position Statement Advisory Panel
Aug 29, 2018·Przegla̜d menopauzalny = Menopause review·Tomasz Paszkowski, Violetta Skrzypulec-Plinta
Feb 12, 2019·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Tomas FaitPedro-Antonio Regidor
Aug 31, 2019·Medicina·Pasquale De FranciscisAntonio Schiattarella

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Citations

Sep 26, 2020·International Journal of Environmental Research and Public Health·EunHee NohEunSurk Yi
Nov 21, 2020·International Journal of Environmental Research and Public Health·Kisook Kim
Oct 22, 2020·Current Pharmaceutical Design·Viswanath Das, Juan Bautista De Sanctis
Mar 7, 2021·International Journal of Environmental Research and Public Health·Hung-Tse ChouWan-Yi Ho
May 1, 2021·Antioxidants·Antonio SchiattarellaGianluca Rizzo
Jun 3, 2021·International Journal of Environmental Research and Public Health·Wiesław KanadysKrzysztof Kanecki
Jul 27, 2021·Expert Opinion on Drug Safety·Pasquale De FranciscisNicola Colacurci

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