Non-hospital delivery and permanent congenital and early-onset hearing loss in a developing country
Abstract
The objective of this study was to determine the role of non-hospital delivery and other risk factors for permanent congenital and early-onset hearing loss (PCEHL) in a developing country. Matched case-control study. Four primary healthcare centres in inner-city Lagos, Nigeria. Fifty-six infants with PCEHL and 280 normal hearing controls matched for age and sex from a population of infants not older than 3 months attending Bacille de Calmette-Guérin immunisation clinics. Conditional logistic regression analyses of infant and maternal characteristics associated with PCEHL, and the evaluation of population exposure to each risk factor. Adjusted matched odds ratios and population attributable risk percent (PAR%). Children with PCEHL were significantly more likely to be first born (OR 1.9, 95% CI 1.1-3.6) without skilled attendants at birth (OR 2.4, 95% CI 1.3-4.5) and have a history of neonatal jaundice requiring exchange blood transfusion (NNJ/EBT) (OR 9.6, 95% CI 2.4-38.2) but less likely to be small for gestational age (SGA) (OR 0.1, 95% CI 0.0-0.5). After controlling for other covariates, the absence of skilled attendants at birth (OR 4.2, 95% CI 2.0-8.6) and NNJ/EBT (OR 19.1, 95% CI 4.3-85.5) emerged as predictors of PCEHL, w...Continue Reading
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