PMID: 11333124May 3, 2001Paper

Non-invasive analysis of melanoma thickness by means of dermoscopy: a retrospective study

Melanoma Research
M StanteP Carli

Abstract

Epiluminescence microscopy (ELM), or dermatoscopy, is a non-invasive technique for the diagnosis of cutaneous melanoma that may play a role in the non-invasive, preoperative assessment of melanoma thickness. This study investigated the correlation between the frequency of appearance of some standard ELM criteria and the histological thickness of melanomas. In addition, the possible role of the total dermoscopic score (TDS) according to ABCD rule of dermoscopy as a predictor of melanoma thickness was analysed. The dermoscopic images of 84 cutaneous melanomas were retrospectively investigated to evaluate the presence of 10 standard ELM criteria, and for each lesion the TDS was established (with observers blinded as to the tumour thickness). A statistically significant association was found between the presence of an irregular pigment network and melanomas with a Breslow index equal to or lower than 0.75 mm (positive predictive value of 68%); in contrast, radial streaming, atypical vascular pattern and grey-blue areas were associated with melanomas > 0.75 mm (positive predictive values of 77%, 65% and 70%, respectively). Of the melanomas thinner than 0.76 mm, 82% showed a TDS lower than 6.80 (optimized cut-off point), while 79% of...Continue Reading

References

Sep 9, 1992·JAMA : the Journal of the American Medical Association
Apr 1, 1994·Journal of the American Academy of Dermatology·F NachbarG Plewig
Aug 1, 1993·The American Journal of Dermatopathology·S YadavC Grin-Jorgensen
Jun 1, 1993·The British Journal of Surgery·G T NeadesK Horgan
Apr 1, 1996·Journal of the American Academy of Dermatology·B F O'DonnellC Billingham
Jul 1, 1997·Journal of the American Academy of Dermatology·G ArgenzianoM Delfino
Jan 13, 1999·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·P CarliG Dosi
Jan 28, 1999·Journal of the American Academy of Dermatology·G ArgenzianoM Delfino
Apr 3, 1999·Journal of the American Academy of Dermatology·H KittlerM Binder
Aug 23, 2000·Journal of the American Academy of Dermatology·P CarliB Giannotti
Jun 1, 1951·The Journal of Investigative Dermatology·L GOLDMAN

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Citations

Jun 21, 2002·Clinics in Dermatology·Vincenzo De Giorgi, Paolo Carli
Jun 21, 2002·Clinics in Dermatology·Giovanni M GaetaAdone Baroni
Apr 18, 2001·Journal of the European Academy of Dermatology and Venereology : JEADV·P CarliB Giannotti
Feb 4, 2006·The American Journal of Dermatopathology·Gisele Gargantini RezzeGilles Landman
Mar 15, 2005·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Paolo CarliVincenzo De Giorgi
Nov 1, 2013·Anais Brasileiros De Dermatologia·Vanessa Priscilla Martins da SilvaGabriella Di Giunta
Feb 28, 2014·International Journal of Biomedical Imaging·Ammara Masood, Adel Ali Al-Jumaily
Mar 8, 2012·Melanoma Research·Stefania SeidenariGiuseppe Argenziano
Apr 30, 2010·The British Journal of Dermatology·S SeidenariG Pellacani
Jan 5, 2011·The Australasian Journal of Dermatology·Alessandro Di StefaniRainer Hofmann-Wellenhof
Mar 13, 2012·The British Journal of Dermatology·P PralongL Thomas
Dec 17, 2015·IEEE Transactions on Medical Imaging·Aurora SaezCesar Hervas-Martinez
Nov 25, 2014·The British Journal of Dermatology·T González-ÁlvarezS Puig
Jun 2, 2012·Dermatology : International Journal for Clinical and Investigative Dermatology·Stefania SeidenariCristina Magnoni
Sep 17, 2015·Anais Brasileiros De Dermatologia·Fatma Pelin CengizRainer Hofmann Wellenhof
Dec 8, 2019·Pigment Cell & Melanoma Research·Adriana SannaGöran Jönsson
Oct 16, 2018·Journal of the American Academy of Dermatology·Oriol YélamosAshfaq A Marghoob
Jan 29, 2021·Journal of the European Academy of Dermatology and Venereology : JEADV·O ReiterA A Marghoob
Feb 28, 2021·Anais Brasileiros De Dermatologia·Fernanda Marques TrindadeFlávia Vasques Bittencourt
Dec 2, 2020·Actas dermo-sifiliográficas·M M Martínez-PivaL D Mazzuoccolo

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