PMID: 3746148Jul 1, 1986Paper

Non-invasive detection of coronary artery disease by body surface electrocardiographic mapping after dipyridamole infusion

Journal of Electrocardiology
K IkedaS Yasui

Abstract

Electrocardiographic changes after dipyridamole infusion (0.568 mg/kg/4 min) were studied in 41 patients with coronary artery disease and compared with those after submaximal treadmill exercise by use of the body surface mapping technique. Patients were divided into three groups; 19 patients without myocardial infarction (non-MI group), 14 with anterior infarction (ANT-MI) and eight with inferior infarction (INF-MI). Eighty-seven unipolar electrocardiograms (ECGs) distributed over the entire thoracic surface were simultaneously recorded. After dipyridamole, ischemic ST-segment depression (0.05 mV or more) was observed in 84% of the non-MI group, 29% of the ANT-MI group, 63% of the INF-MI group and 61% of the total population. Exercise-induced ST depression was observed in 84% of the non-MI group, 43% of the ANT-MI group, 38% of the INF-MI group and 61% of the total. For individual patients, there were no obvious differences between the body surface distribution of ST depression in both tests. The increase in pressure rate product after dipyridamole was significantly less than that during the treadmill exercise. The data suggest that the dipyridamole-induced myocardial ischemia is caused by the inhomogenous distribution of myoca...Continue Reading

References

May 1, 1968·Circulation Research·W M Fam, M McGregor
Apr 1, 1982·Clinical Cardiology·L DeAmbroggiM Radice
Jul 1, 1981·The American Journal of Cardiology·G J Gross, D C Warltier

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Citations

Jan 1, 1995·Journal of Electrocardiology·R H Selvester
Nov 25, 2003·Medical Engineering & Physics·Michael J Lewis
Jul 31, 1998·Journal of Cardiovascular Electrophysiology·B TaccardiY Vyhmeister
Jan 1, 1990·Journal of Electrocardiology·B Taccardi
Feb 15, 1992·The American Journal of Cardiology·F S VillanuevaG A Beller

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